Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: “Stealth Dissemination” of Macrophage-Tumor Cell Fusions Cultured from Blood of Patients with Pancreatic Ductal Adenocarcinoma

PROVIDER: PRJNA389267 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5650200.fastq.gz	Fastqsanger.gz
	SRR5650210.fastq.gz	Fastqsanger.gz
	SRR5650220.fastq.gz	Fastqsanger.gz
	SRR5650230.fastq.gz	Fastqsanger.gz
	SRR5650240.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 308

Similar Datasets

Transcriptome profile of peripheral blood from pancreatic ductal adenocarcinoma patients

2015-11-04 | GSE74629 | GEO

Transcriptome profile of peripheral blood from pancreatic ductal adenocarcinoma patients

Project description:Analysis of expression profile of peripheral blood from pancreatic ductal adenocarcinoma patients RNA expression profile of peripheral blood from pancreatic ductal adenocarcinoma patients Total RNA was isolated from peripheral blood. 36 patients with unresectable PDAC were recruited. The diagnosis of PDAC was based on clinical evaluation and imaging studies, which were histologically confirmed by surgery or imaging-guided biopsy. 14 gender, age, and habits matched healthy controls were also included. A total of 1000 ng of total RNA was processed using Illumina TotalPrep RNA Amplification Kit. Hybridization of human samples was performed on Illumina Human-HT12 Version 4.

2015-11-04 | E-GEOD-74629 | biostudies-arrayexpress

DNA methylation analysis using Illumina 450K BeadChip of 7 pancreatic ductal adenocarcinoma patients

Project description:Genome-wide DNA methylation profiling of normal and tumor tissue samples of 7 pancreatic ductal adenocarcinoma patients.

2022-11-09 | GSE181740 | GEO

Antithetical NFATc1-Sox2 and p53-miR-200 signalling networks governs pancreatic cancer cell plasticity and tumour progression

Project description:Pancreatic ductal adenocarcinoma (PDAC) cells undergo epithelial mesenchymal transdifferentiation (EMT) in adaption to environmental cues, including inflammation, a process that combines tumour cell dedifferentiation with dissemination and acquisition of stemness features. However, the mechanisms coupling inflammation-induced signalling pathways with EMT and stemness remain largely unknown. Here, we reveal the inflammation-induced transcription factor NFATc1 as a central regulator of pancreatic cancer cell plasticity.

2015-02-10 | E-MTAB-2324 | biostudies-arrayexpress

Homo sapiens

Project description:Transcriptome profile of peripheral blood from pancreatic ductal adenocarcinoma patients

| PRJNA301037 | ENA

RNA-seq of purified human pancreatic dedifferentiated acinar cells and duct cells

Project description:Pancreatic acinar cells can dedifferentiate upon tissue injury and acquire ductal characteristics. This acquisition of duct cell features is critical in tumor development. Nevertheless, duct cells themselves are less prone for development of PDAC (pancreatic ductal adenocarcinoma) than dedifferentiated acini. We aimed to clarify which genes are unique for dedifferentiated acini. Mixed exocrine preparations of acinar and duct cells were obtained from human pancreatic donor organs and cultured to induce dedifferentiation. We lineage-labeled and FACS-purified these human dedifferentiated acinar cells and compared them to duct cells from the same donor (n=5).

2021-06-17 | E-MTAB-9386 | biostudies-arrayexpress

Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma

Project description:Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma

2023-09-02 | PXD045063 |

DNA methylation sequencing of human pancreatic acinar and ductal cells [Bisulfite-seq]

Project description:Flow-sorted pancreatic acinar and ductal cells from fresh human pancreatic exocrine tissue were subjected to molecular characterization to identify lineage-specific expression and epigenetic properties. Cells of both lineages were cultured and transformed via lentiviral mutation to form pancreatic ductal adenocarcinoma.

2023-11-27 | GSE223153 | GEO

RNA sequencing of human pancreatic acinar and ductal cells

2023-11-27 | GSE222990 | GEO

Homo sapiens

Project description:Expression data from peripheral blood in pancreatic ductal adenocarcinoma (PDAC) patients

| PRJNA214906 | ENA