Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: The response of Anammox consortia to acetate stimuli

PROVIDER: PRJNA391007 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5712693_1.fastq.gz	Fastqsanger.gz
	SRR5712693_2.fastq.gz	Fastqsanger.gz
	SRR5712694_1.fastq.gz	Fastqsanger.gz
	SRR5712694_2.fastq.gz	Fastqsanger.gz
	SRR5712695_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Unraveling biomolecular and ecological mechanisms underlying the response of anammox consortia under xenobiotic stress by multi-omics strategy

Project description:Anaerobic ammonium oxidation (anammox) emerges as a sustainable solution for nitrogen removal in sewage, but it is susceptible to stress induced by xenobiotics that are ubiquitous in sewage. Despite wide recognition of this critical issue, a comprehensive understanding of the molecular and ecological mechanisms underlying the response of anammox consortia to xenobiotic stress remain elusive. Here, we integrated multi-omics approaches with biofilm reactor operation to unravel how bisphenol A (BPA, a representative xenobiotic) perturbs anammox consortia across environmentally relevant concentrations. We show that anammox consortia tolerated low BPA levels (0.2–2 mg/L), where nitrogen removal efficiency transiently declined and subsequently recovered, aided by a 30.9% increase in quorum-sensing (QS) signal C6-HSL. By contrast, exposure to ≥10 mg/L BPA caused severe and irreversible inhibition, with total inorganic nitrogen removal dropping to 17.8%. High BPA concentrations suppressed QS signaling, intensified oxidative stress, and compromised membrane integrity, leading to enzymatic inhibition and transcriptional repression of anammox functional genes. Multi-omics evidence revealed that BPA stress also promoted horizontal transfer of the BPA-degrading gene bisdA via extracellular DNA, suggesting a new community-level adaptive mechanism. Metagenomic and metabolomic analyses further indicated BPA-driven restructuring of microbial networks, namely high BPA levels favored denitrifiers and BPA degraders while suppressing anammox bacteria, and triggered metabolic reprogramming toward xenobiotic degradation at the expense of nucleotide and amino acid biosynthesis. Together, these findings reveal a multifaceted collapse mechanism of anammox under BPA stress, providing a mechanistic basis for designing strategies to safeguard microbial nitrogen removal in xenobiotic-laden wastewaters.

2026-03-27 | MTBLS14153 | MetaboLights

Project description:Response of Anammox Consortia to NPs

| PRJNA1098598 | ENA

Mechanobiological mechanism of anammox bacteria towards flow shear stress

Project description:4D label-free metaproteomic technique was used to reveal the protein expressions of anammox consortia under different flow shear stress (represented by different stirring speeds: 40, 120, and 200 rpm).

| PXD079362 |

Project description:Anammox consortia senquencing

| PRJNA760253 | ENA

Project description:Anammox consortia structure

| PRJNA1078103 | ENA

Project description:acetate feeding anammox metagenomics

| PRJNA679146 | ENA

Effects of Fe(II) on anammox community activity and functional genes expression

Project description:Four Fe(II) concentrations (0.03, 0.09, 0.12 & 0.75 mM) were tested to investigate the stimulation and inhibition effects of ferrous iron on anammox bacterial activity. RNAs were extracted from the cultures, and the synthesized cDNAs by reverse transcription were used to carry out GeoChip analysis, by which the functional communities and expression level differences in functional genes under different Fe(II) concentrations conditions were obtained, and the response of anammox bacteria to Fe(II) stimulation and inhibition are speculated.

2020-08-28 | GSE120704 | GEO

Project description:Anammox consortia community in reactors

| PRJNA397620 | ENA

Project description:Metabolic interactions in anammox consortia

| PRJNA789415 | ENA

Project description:Anammox consortia community after storing

| PRJNA448561 | ENA