Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Phaeobacter italicus

ABSTRACT: Gene expression prpfoling of the pathogen, Nautella italica R11, in response to its macroalagl host

PROVIDER: PRJNA397905 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR5925780.fastq.gz	Fastqsanger.gz
	SRR5925790.fastq.gz	Fastqsanger.gz
	SRR5925781.fastq.gz	Fastqsanger.gz
	SRR5925791.fastq.gz	Fastqsanger.gz
	SRR5925782.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Phaeobacter italicus

Project description:Nautella italica overview

| PRJNA321770 | ENA

Gene expression prpfoling of the pathogen, Nautella italica R11, in response to its macroalagl host

Project description:RNA-Seq analysis of bacterial cultures of Nautella italica R11, Wild type strain and a RaiR gene disruption strain in the presence and absence of the red macroalga Delisea pulchra

2017-11-09 | GSE102507 | GEO

Phaeobacter italicus

Project description:Draft genome sequencing of Nautella italica strain LMG24365

| PRJDB4510 | ENA

Phaeobacter italicus strain:dsm 26436

Project description:Nautella italica DSM 26436 genome sequencing

| PRJNA303500 | ENA

Project description:Nautella italica DSM 26436

| PRJEB17312 | ENA

Dual spatially resolved transcriptomics for SARS-CoV-2 host-pathogen colocalization studies in humans

Project description:To advance our understanding of cellular host-pathogen interactions, technologies that facilitate the co-capture of both host and pathogen spatial transcriptome information are needed. Here, we present an approach to simultaneously capture host and pathogen spatial gene expression information from the same formalin-fixed paraffin embedded (FFPE) tissue section using the spatial transcriptomics technology. We applied the method to COVID-19 patient lung samples and enabled the dual detection of human and SARS-CoV-2 transcriptomes at 55 Ã‚Âµm resolution. We validated our spatial detection of SARS-CoV-2 and identified an average specificity of 94.92% in comparison to RNAScope and 82.20% in comparison to in situ sequencing (ISS). COVID-19 tissues showed an upregulation of host immune response, such as increased expression of inflammatory cytokines, lymphocyte and fibroblast markers. Our colocalization analysis revealed that SARS-CoV-2+ spots presented shifts in host RNA metabolism, autophagy, NFÃŽÂºB, and interferon response pathways. Future applications of our approach will enable new insights into host response to pathogen infection through the simultaneous, unbiased detection of two transcriptomes.

| EGAS00001006186 | EGA

Gene Array to Predict Bacterial Infection with in Respiratory Illness

Project description:<p>Accurate tests for microbiologic diagnosis of lower respiratory tract infections (LRTI) are needed. Gene expression profiling of whole blood represents a powerful new approach for analysis of the host response during respiratory infection that can be used to supplement pathogen detection testing. Using qPCR, we prospectively validated the differential expression of 10 genes previously shown to discriminate bacterial and non-bacterial LRTI confirming the utility of this approach. In addition, a novel approach using RNAseq analysis identified 141 genes differentially expressed in LRTI subjects with bacterial infection. Using "pathway-informed" dimension reduction, we identified a novel 11 gene set (selected from lymphocyte, α-linoleic acid metabolism, and IGF regulation pathways) and demonstrated a predictive accuracy for bacterial LRTI (nested CV-AUC=0.87). RNAseq represents a new and an unbiased tool to evaluate host gene expression for the diagnosis of LRTI.</p>

| phs001248 | dbGaP

Nautella italica CECT 7321

Project description:Whole genome sequencing of Nautella italica CECT 7321

| PRJEB9393 | ENA

Phaeobacter italicus strain:JN-W1

Project description:Phaeobacter italicus strain:JN-W1 Genome sequencing

| PRJNA1115903 | ENA

Calliptamus italicus

Project description:Calliptamus italicus Transcriptome or Gene expression

| PRJNA412122 | ENA