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Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS

ABSTRACT: Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS

PROVIDER: PRJNA412256 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR6078620_1.fastq.gz	Fastqsanger.gz
	SRR6078620_2.fastq.gz	Fastqsanger.gz
	SRR6078621_1.fastq.gz	Fastqsanger.gz
	SRR6078621_2.fastq.gz	Fastqsanger.gz
	SRR6078622_1.fastq.gz	Fastqsanger.gz

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Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS

Project description:RNA-sequencing was performed to gain insight into the mechanism responsible for the mesenchymal-to-epithelial transition (MET) induced by loss of long non-coding RNA (lncRNA) DNM3OS in SKOV3 ovarian cancer cells. Following siRNA-mediated knockdown of DNM3OS or non-targeting control, RNA-sequencing was performed. This high-throughput data revealed knockdown of DNM3OS down-regulated the expression of genes and pathways known to induce EMT in ovarian cancer.

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