Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Aerosol metagenome

ABSTRACT: Bioaerosols along transported pathway of Asian dust

PROVIDER: PRJNA413598 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6153500.fastq.gz	Fastqsanger.gz
	SRR6153510.fastq.gz	Fastqsanger.gz
	SRR6153520.fastq.gz	Fastqsanger.gz
	SRR6153501.fastq.gz	Fastqsanger.gz
	SRR6153511.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 22

Similar Datasets

aerosol metagenome

Project description:Vertical distributions of airborne microorganisms in Asian dust (Kosa) source region of Taklamakan and Gobi Deserts.

| PRJDB7149 | ENA

aerosol metagenome

Project description:hospital bioaerosols Targeted Locus (Loci)

| PRJNA294282 | ENA

aerosol metagenome

Project description:Characterization of Bacterial Communities in Bioaerosols over Bohai Sea and Yellow Sea in spring

| PRJNA615064 | ENA

aerosol metagenome

Project description:Characterization of Bacterial Communities in Bioaerosols over Bohai Sea and Yellow Sea in summer

| PRJNA615283 | ENA

aerosol metagenome

Project description:Effects of dust on bacterial communities in Lanzhou and Qingdao

| PRJNA610122 | ENA

Aerosol metagenome

Project description:Bioaerosols in the Athens Metro: Metagenetic insights into the PM10 microbiome in a naturally ventilated subway station

| PRJNA597004 | ENA

aerosol metagenome

Project description:Bacterial Community characteristics in marine bioaerosols on the Bohai Sea, Yellow Sea and Northwest Pacific in spring

| PRJNA429542 | ENA

aerosol metagenome

Project description:Characteristics of bacterial bioaerosols at Toyama and Yokohama in Japan as assessed by eight-stage Andersen sampler and Illumina MiSeq sequencing

| PRJDB8920 | ENA

Murine Legionella pneumophilaInfection by Bioaerosol Inhalation in a Madison Aerosol Chamber Leads to Similar Disease Outcomes and Host Transcriptomic Responses as Intranasal Inoculation While Allowing for Bioaerosol Analysis

Project description:Legionnaire’s Disease is a growing concern for the United States and Europe, with disease incidences rising 6-fold since 2002. These recorded cases are increasingly associated with antibiotic resistant Legionella pneumophila, the causative agent of Legionnaire’s Disease and overall Legionellosis. With this, the need to study L. pneumophilainfections has never been greater. Current methodology for Legionella pneumophila infection studies often revolves around either artificial administration using intranasal or intratracheal delivery, semi-authentic delivery using bioaerosols and individual delivery systems (i.e. nose cones), or the burgeoning field of authentic exposure scenarios using aerosol generating showerhead devices. Here, we developed an alternative method using a Madison Aerosol Chamber as a means of generating and delivering bioaerosols in mice. We show that bioaerosol delivery using the Aerosol Exposure Chamber is very effective at exposing mice to various doses of L. pneumophila. RNASeq analyses revealed a robust immune response to bioaerosol delivered L. pneumophila comprising of activations of classical markers of infection and inflammation, including Cxcl and Ccl family genes and Il-1β. Similar gene expression profiles were observed when animals were intranasally exposed to L. pneumophila. Intranasal delivery resulted in a shorter duration of activation of several genes, indicating a lack of realistic infection response. Taken together, this evidence shows that our system delivers similar, if not better, results than intranasal inoculation while allowing researchers to study bioaerosol generation and delivery mechanisms simultaneously, critical factors for studying Legionella pneumophila infection. Such a new approach will allow for more accurate investigations to understand the effects of inhaling to Legionella contaminated drinking water.

2023-10-01 | GSE241094 | GEO

aerosol metagenome

Project description:Long-range transport of airborne bacteria by westerly winds

| PRJDB13520 | ENA