Project description:A single-centre, randomized, 2-arm clinical trial comparing follow-up consisting of tumour-specific Electronic Patient-Reported Outcomes (ePROs) with targeted symptom management versus standard of care follow-up during neoadjuvant/adjuvant systemic therapy

| 2385533 | ecrin-mdr-crc

Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)

Project description:This is a proof-of-concept pilot randomized clinical trial to test the feasibility of the innovative Patient-Reported Outcomes-Informed Symptom Management System (PRISMS) to enhance personalized supportive care for cancer patients and caregivers during post-treatment care transition.

| 2347191 | ecrin-mdr-crc

Self-Reported Race as a Determinant of Differential Methylation in Peripheral Artery Disease

Project description:Peripheral Artery Disease (PAD) is a manifestation of atherosclerosis within the lower extremities that affects approximately 10 million people in the United States. Despite the rising prevalence of PAD, Black Americans are disproportionately affected and experience worse outcomes, including higher rates of limb loss compared to White counterparts. To dissect mechanisms within PAD, we performed DNA methylation analysis utilizing methyl-binding domain-capture sequencing. Within the DNA methylation profiles, we observe a large driver of variation is self-reported race. Specifically, samples separate into White and Black groups. Interestingly, when comparing PAD to Control samples within each self-reported racial group, there are different differentially methylated CpGs between the two groups. This suggests that the methylation landscape both at baseline and in disease is different based on self-reported racial background and could begin to explain some of the differences we see in downstream outcomes between White and Black Americans.

2025-12-04 | GSE289487 | GEO

Evaluating the Use of Patient-Reported Outcome Measures for Improving the Inter-Rater Reliability of Common Terminology Criteria for Adverse Event Ratings

Project description:This open randomized trial investigates, if clinicians complete CTCAE ratings differently when receiving patients’ patient-reported outcome (PRO) data prior to their CTCAE completion. The primary objective is to demonstrate superior inter-rater reliability of CTCAE ratings from physicians relying on EORTC PRO data as additional data source over traditional CTCAE ratings not including PRO information.

| 2314534 | ecrin-mdr-crc

A Period1 inducer specifically advances circadian clock in mice

Project description:A Period1 inducer specifically advances circadian clock in mice

| PRJNA1276469 | ENA

Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes

Project description:This study examines at-home monitoring of patient-generated phsyiologic health data and patient-reported outcomes. Patient-generated health data using at-home monitoring devices and smart device applications are used more and more to measure value and quality in cancer care. This trial may show whether at-home monitoring programs can improve the care of patients after hospital discharge from surgery.

| 2347952 | ecrin-mdr-crc

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data