Project description:To elucidate whether Faecalibacterium prausnitzii has effects on intestinal toxicity induced by immune checkpoint inhibitors, we performed RNA-seq analysis of colon tissues of mice receiving DSS, DSS+ICB and DSS+ICB+F. prausnitzii gavage to compare the gene expression profiles.
Project description:We explored the transcriptional response of Faecalibacterium prausnitzii A2-165 when exposed to cell-free supernatants from different Lactobacillus, Streptococcus and Lactococcus strains. For that, we sequenced its RNA and looked for significant differences in the expression levels among the supernatants groups.
