Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The impact of DSF and C23 on P. aeruginosa physiology

ABSTRACT: The impact of DSF and C23 on P. aeruginosa physiology

PROVIDER: PRJNA432916 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

The impact of DSF and C23 on P. aeruginosa physiology

Project description:To verify the imapct of DSF and C23 on P. aeruginosa during infection We used microarray to compare the effects of adding either DSF alone or DSF with C23 on P. aeruginosa gene expression during mouse lung infection relative to the gene expression of P. aeruginosa in the mouse lung with no compound.

2018-09-30 | GSE110126 | GEO

Impact of carbon source supplementations on Pseudomonas aeruginosa physiology

Project description:By a global proteomic approach and phenotypic assays, we investigated the impact of various carbon source supplementations (glucose, glutamate, succinate and citrate) on the physiology P. aeruginosa PA14 strain. A total of 581 proteins were identified as differentially expressed in the 4 conditions. Most of them were more abundant in citrate supplementation and were involved in virulence, motility, biofilm development and antibiotic resistance.

2022-05-08 | PXD030421 | Pride

Physiology of Pseudomonas aeruginosa cells without major RND-type multidrug efflux pumps

Project description:Purpose: In this study, we analyzed how P. aeruginosa physiology is adapted to the lack of RND-mediated efflux activities. Methods: In this study, we use PΔ6 cells to analyze how P. aeruginosa changes its physiology in response to the lack of efflux pumps and increased permeability of the cell envelope. We compared the transcriptomes of the exponentially growing and stationary PΔ6 and its parent PAO1 cells and identified the cellular functions stressed by the lack of active efflux. High quality total RNA was further processed by removing 23S and 16S rRNAs using the Illumina Ribo-Zero Plus rRNA Depletion kit. Samples were analyzed in duplicate using Illumina MiSeq. Raw data for each sample was analyzed using CLC Genomics Workbench version 12.0.1 software (QIAGEN Aarhus, Denmark). Results: P. aeruginosa PΔ6 strain lacking six best characterized RND pumps activates a specific adaptation response that involves significant changes in expression of specific subset of genes encoding e.g. several transport systems, quorum sensing or iron acquisition. Conclusion: Our results suggest that all changes we observe serve to protect the cell envelope of efflux-deficient P. aeruginosa.

2021-04-30 | GSE169036 | GEO

The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction

Project description:The goal of this study was to determine the impact of metal deprivation (such as the metal deprivation induced by calprotectin treatment) on the physiology of Pseudomonas aeruginosa under multiple growth conditions. The RNA-seq analysis was designed to reveal the impact of calprotectin treatment on P. aeruginosa physiology during planktonic growth.

2016-09-29 | GSE81065 | GEO

DSF effects on Arabidopsis

Project description:To investigate the effects of DSF on Arabidopsis in Xcc infecction, we used 2 μM DSF pretreated the roos of Arabidopsis for 48h and then inoculated with Xcc, We then performed gene expression profiling analysis using data obtained from RNA-seq of pretreated/unpretreated at two time points (inoculated with Xcc or not)

2023-04-15 | GSE229511 | GEO

dsf

Project description:Drosophila melanogaster dsf, dissatisfaction, is differentially expressed in 4 experiment(s);

| FBgn0015381 | ExpressionAtlas

dsf

Project description:Drosophila melanogaster dsf, dissatisfaction, is expressed in 3 baseline experiment(s);

| FBgn0015381 | ExpressionAtlas

DSF effects on Arabidopsis

Project description:DSF effects on Arabidopsis

| PRJNA954814 | ENA

Expression data from meningioma cell after DSF and Cu treatment

Project description:We demonstrate that DSF/Cu treatment reduced meningioma cell viability and increased intracellular ER stress. We used microarrays to analyze the DSF/Cu regulated gene expression.

2024-02-11 | GSE196689 | GEO

IMPACT

Project description:Oryctolagus cuniculus IMPACT, Oryctolagus cuniculus impact RWD domain protein (IMPACT), mRNA. [Source:RefSeq mRNA;Acc:NM_001082640], is expressed in 1 baseline experiment(s);

| ENSOCUG00000013901 | ExpressionAtlas

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data