Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Vertically inherited structural variations shape the genome of experimentally evolved Bartonella

PROVIDER: PRJNA439376 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR6873510_1.fastq.gz	Fastqsanger.gz
	SRR6873520_1.fastq.gz	Fastqsanger.gz
	SRR6873520_2.fastq.gz	Fastqsanger.gz
	SRR6873530_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 53

Similar Datasets

Project description:Genomes of vertically inherited stinkbug symbionts

| PRJNA413893 | ENA

Project description:Experimentally evolved yeast isolates

| PRJNA634573 | ENA

Staphylococcus aureus

Project description:Experimentally evolved SA population

| PRJDB13481 | ENA

Pseudomonas aeruginosa PAO1

Project description:Experimentally evolved PA population

| PRJDB13465 | ENA

Two novel Bartonella (sub)species isolated from edible dormice (Glis glis): Hints of cultivation stress-induced genomic changes

Project description:Bartonelloses are neglected emerging infectious diseases caused by facultatively intracellular bacteria transmitted between vertebrate hosts by various arthropod vectors. The highest diversity of Bartonella species has been identified in rodents. Within this study we focused on the edible dormouse (Glis glis), a rodent with unique life-history traits that often enters households and whose possible role in the epidemiology of Bartonella infections had been previously unknown. We identified and cultivated two distinct Bartonella sub(species) significantly diverging from previously described species, which were characterized using growth characteristics, biochemical tests, and various molecular techniques including also proteomics. Two novel (sub)species were described: Bartonella grahamii subsp. shimonis subsp. nov. and Bartonella gliris sp. nov.We sequenced two individual strains per each described (sub)species. During exploratory genomic analyses comparing two genotypes ultimately belonging to the same species, both factually and most importantly even spatiotemporally, we noticed unexpectedly significant structural variation between them. We found that most of the detected structural variants could be explained either by prophage excision or integration. Based on a detailed study of one such event, we argue that prophage deletion represents the most probable explanation of the observed phenomena.Moreover, in one strain of Bartonella grahamii subsp. shimonis subsp. nov. we identified a deletion related to Bartonella Adhesin A, a major pathogenicity factor that modulates bacteria-host interactions. Altogether, our results suggest that even a limited number of passages induced sufficient selective pressure to promote significant changes at the level of the genome.

2023-10-28 | PXD046060 | Pride

Project description:Genetics of experimentally evolved multicellularity

| PRJNA479583 | ENA

Saccharomyces cerevisiae S288C

Project description:Experimentally-evolved Saccharomyces cerevisiae clones

| PRJNA784975 | ENA

Project description:structural variations(SVs)

| PRJNA971876 | ENA

BWW

Project description:Recombination and large structural variations shape the genomes of interspecific edible bananas.

| PRJEB28077 | ENA

Project description:Pleiotropy in experimentally-evolved yeast clones