Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Tumor immune evasion arises through loss of TNF sensitivity

ABSTRACT: Tumor immune evasion arises through loss of TNF sensitivity

PROVIDER: PRJNA445390 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6884920.fastq.gz	Fastqsanger.gz
	SRR6884930.fastq.gz	Fastqsanger.gz
	SRR6884940.fastq.gz	Fastqsanger.gz
	SRR6884950.fastq.gz	Fastqsanger.gz
	SRR6884960.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 52

Similar Datasets

Tumor immune evasion arises through loss of TNF sensitivity [MC38]

Project description:Tumor immune evasion arises through loss of TNF sensitivity [MC38]

| PRJNA445399 | ENA

Tumor immune evasion arises through loss of TNF sensitivity [Ado]

Project description:Tumor immune evasion arises through loss of TNF sensitivity [Ado]

| PRJNA445398 | ENA

Tumor immune evasion arises through loss of TNF sensitivity [MC38]

Project description:Investigation of the transcriptional response to TNF and Interferon gamma or T cells

2018-04-01 | GSE112252 | GEO

Tumor immune evasion arises through loss of TNF sensitivity [Ado]

Project description:Investigation of the transcriptional response of wild type or Ado knockout MC38 cells to TNF

2018-04-01 | GSE112251 | GEO

Tumor immune evasion arises through loss of TNF sensitivity

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-04-01 | GSE112253 | GEO

Genome-wide CRISPR screen to identfy immune evasion genes in pancreatic cancer

Project description:Here we systematically dissected PDA intrinsic mechanisms of immune evasion by in vitro and in vivo CRISPR screening. Beyond the conserved set of genes regulating anti-cancer immunity we identified Rnf31 and Vps4b as essential factors required for escaping CD8+ T cell-killing. While the absence of Rnf31 induced sensitivity to T cell killing through TNF-mediated apoptosis in murine cancer cells and human PDA organoids, loss of Vps4b abrogated functional autophagy, resulting in accumulation of CD8+ T cell-derived granzyme B and subsequent tumor cell lysis.

2021-07-27 | GSE180834 | GEO

SULT2B11b regulates sensitivity to TNF-mediated cell death in Prostate Cancer

Project description:SULT2B11b regulates sensitivity to TNF-mediated cell death in Prostate Cancer

| PRJNA482003 | ENA

Chronic viral mimicry induction following p53 loss promotes immune evasion

Project description:Chronic viral mimicry induction following p53 loss promotes immune evasion

| PRJNA896220 | ENA

Chronic viral mimicry induction following p53 loss promotes immune evasion [scRNASeq]

Project description:Chronic viral mimicry induction following p53 loss promotes immune evasion [scRNASeq]

| PRJNA896215 | ENA

Chronic viral mimicry induction following p53 loss promotes immune evasion [CUTandRUN]

Project description:Chronic viral mimicry induction following p53 loss promotes immune evasion [CUTandRUN]