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Anaerostipes hadrus

ABSTRACT: butyrate-producing bacterium SSC/2 overview

PROVIDER: PRJNA46177 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	DRR457762_1.fastq.gz	Fastqsanger.gz

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A novel, butyrate-producing Gram-positive bacterium from the human gut, Hoskinsella mucinolytica, selectively targets N-acetylhexosamine sugars in host mucins

Project description:We used culturing of fecal sample enrichments on solid medium containing gastric mucin as the main carbon source to isolate a novel bacterium that is largely restricted to using the N-acetylglucosamine and N-acetylgalactosamine sugars from mucin. This butyrate-producing bacterium accesses these sugars from both polymeric gastric mucin and chemically released oligosaccharides and has a genome with correspondingly restricted carbohydrate-active enzyme content. Sequencing data was curated to determine gene expression profiles when comparing N-acetylgalactosamine, N-acetylglucosamine, gastric mucin oligosaccharides and cellobiose.

2024-12-01 | GSE267699 | GEO

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