Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: mouse fecal microbiota Targeted loci

PROVIDER: PRJNA478451 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7453120.fastq.gz	Fastqsanger.gz
	SRR7453120_1.fastq.gz	Fastqsanger.gz
	SRR7453120_2.fastq.gz	Fastqsanger.gz
	SRR7453130.fastq.gz	Fastqsanger.gz
	SRR7453130_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 144

Similar Datasets

Mus musculus

Project description:Mouse fecal microbiota Targeted loci

| PRJNA316140 | ENA

Mus musculus

Project description:mouse fecal microbiota Targeted loci (16S)

| PRJNA478558 | ENA

Mus musculus

Project description:Mouse cecal microbiota Targeted loci

| PRJNA315894 | ENA

Mus musculus

Project description:Bacterial component of the fecal microbiota from different mouse models Targeted loci

| PRJNA1211296 | ENA

Mus musculus

Project description:mouse cecal microbiota Targeted loci (16S)

| PRJNA478211 | ENA

Mus musculus

Project description:Fecal microbiome from different mouse models Targeted loci

| PRJNA1209992 | ENA

Mus musculus

Project description:Fecal microbiota of different Mutant Mouse Resource & Research Centers (MMRRC) strains Targeted loci (16S)

| PRJNA782653 | ENA

Mus musculus

Project description:Fecal microbiota of different Mutant Mouse Resource & Research Centers (MMRRC) strains Targeted loci (16S)

| PRJNA543350 | ENA

Mus musculus

Project description:Fecal microbiota of different Mutant Mouse Resource & Research Centers (MMRRC) strains- Targeted loci (16S)

| PRJNA541964 | ENA

RNA-seq profiling of mouse PGC (Mus musculus)

Project description:PGCs undergo two distinct stages of demethylation before reaching a hypomethylated ground state at E13.5. Stage 1 occurs between E7.25- E9.5 in which PGCs experience a global loss of cytosine methylation. However, discreet loci escape this global loss of methylation and between E10.5-E13.5, stage 2 of demethylation takes place. In this stage these loci are targeted by Tet1 and Tet2 leading to the loss of the remaining methylation and resulting in the epigenetic ground state. Our data shows that Dnmt1 is responsible for maintaining the methylation of loci that escape stage 1 demethylation, and that it functions in a UHRF1 independent manner. Our data further demonstrates that when these loci lose methylation prior to stage 2 it results in early activation of the meiotic program, which leads to precocious differentiation of the germ line resulting in a decreased pool of PGCs in the embryo and subsequent infertility in adult mice.

2016-09-13 | GSE74938 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data