Lynx canadensis
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ABSTRACT:
PROVIDER: PRJNA490577 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Lynx canadensis (Canada Lynx) genome sequencing and assembly, primary haplotype, v1
| PRJNA489107 | ENA
Project description:Lynx canadensis (Canada Lynx) genome sequencing and assembly, alternate haplotype, v1
| PRJNA489108 | ENA
Project description:microRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at post-transcriptional level and play essential roles in fundamental biological processes such as development and metabolism. Here, we perform a comprehensive analysis of miRNAs in the zoonotic parasite E. canadensis G7, one of the causative agents of the neglected disease cystic echinococcosis. Small RNA libraries from protoscoleces and cyst walls of E. canadensis G7 and protoscoleces of E. granulosus sensu stricto G1 were sequenced using Illumina technology. As a result, we found transcriptional evidence of 37 miRNAs thus expanding the miRNA repertoire of E. canadensis G7. Differential expression analysis showed significant regulated miRNAs between life cycle stages of E. canadensis G7. We confirmed the remarkable loss of conserved miRNA families in E. canadensis, reflecting their low morphological complexity and high adaptation to parasitism. This study will provide valuable information for better understanding the complex biology of this parasite and could help to find new potential targets for therapy and/or diagnosis.
2015-02-09 | GSE64705 | GEO
Project description:Abstract Lynx canadensis Kerr, 1792, commonly called the Canada lynx, is a medium size felid and is the second largest of the four species in the genus Lynx. It is distributed throughout the boreal forest of most of Canada and Alaska and across portions of the northern United States. It prefers dense, regenerating coniferous forests with moderate canopy and understory cover. L. canadensis is a snowshoe hare specialist, and its ecology, morphology, and behavior closely reflect that of its main prey. It is listed as “Least Concern” by the International Union for Conservation of Nature and Natural Resources, is on Appendix II of the Convention on International Trade in Endangered Species of Wild Fauna and Flora, and its population size trend is considered stable. However, the status of United States subpopulations, being largely peripheral to the Canadian population, is more tenuous and the species is protected.
| S-EPMC7149466 | biostudies-literature
Project description:microRNAs (miRNAs), a class of small non-coding RNAs, are key regulators of gene expression at post-transcriptional level and play essential roles in fundamental biological processes such as development and metabolism. Here, we perform a comprehensive analysis of miRNAs in the zoonotic parasite E. canadensis G7, one of the causative agents of the neglected disease cystic echinococcosis. Small RNA libraries from protoscoleces and cyst walls of E. canadensis G7 and protoscoleces of E. granulosus sensu stricto G1 were sequenced using Illumina technology. As a result, we found transcriptional evidence of 37 miRNAs thus expanding the miRNA repertoire of E. canadensis G7. Differential expression analysis showed significant regulated miRNAs between life cycle stages of E. canadensis G7. We confirmed the remarkable loss of conserved miRNA families in E. canadensis, reflecting their low morphological complexity and high adaptation to parasitism. This study will provide valuable information for better understanding the complex biology of this parasite and could help to find new potential targets for therapy and/or diagnosis. Small RNA libraries from protoscoleces and cyst walls of E. canadensis G7 and protoscoleces of E. granulosus sensu stricto G1 were sequenced using Illumina technology. For each sample type, two libraries were constructed from two independent samples in order to have biological replicates.
2015-02-09 | E-GEOD-64705 | biostudies-arrayexpress