Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single -cell type transcriptomic and imprintomic analysis in the mouse cerebral cortex

ABSTRACT: Single -cell type transcriptomic and imprintomic analysis in the mouse cerebral cortex

PROVIDER: PRJNA490711 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7826053_1.fastq.gz	Fastqsanger.gz
	SRR7826053_2.fastq.gz	Fastqsanger.gz
	SRR7826054_1.fastq.gz	Fastqsanger.gz
	SRR7826054_2.fastq.gz	Fastqsanger.gz
	SRR7826055_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Single -cell type transcriptomic and imprintomic analysis in the mouse cerebral cortex

Project description:Some imprinted genes were observed in a cell-type-specific manner. However, genome-wide profiling of cell-type-specific genes has not been performed in the brain. We addressed this question and identified cell-type-specific and strain-specific monoallelically expressed genes in the mouse cerebral cortex.

2023-04-17 | GSE119876 | GEO

Single-cell RNA-seq of mouse cerebral cortex

Project description:We have applied a recently developed, highly accurate and sensitive single-cell RNA-seq method (STRT/C1) to perform a molecular census of two regions of the mouse cerebral cortex: the somatosensory cortex and hippocampus CA1. We isolated cells fresh from somatosensory cortex (S1) and hippocampus CA1 area of juvenile (P22 - P32) CD1 mice, 33 males and 34 females. Cells were collected without selection, except that 116 cells were obtained by FACS from 5HT3a-BACEGFP transgenic mice. A total of 76 Fluidigm C1 runs were performed, each attempting 96 cell captures and resulting in 3005 high-quality single-cell cDNAs, containing Unique Molecular Identifiers allowing counting of individual mRNA molecules, even after PCR amplification.

2015-02-20 | E-GEOD-60361 | biostudies-arrayexpress

Niemann-Pick type C1 unfractionated cerebellum and cerebral cortex proteomics

Project description:label-free quantification using 11 week mouse tissue lysates from non fractionated cerebellum and cerebral cortex of wild type and NPC1 null mice.

2018-02-08 | MSV000082042 | MassIVE

Single-Cell Transcriptomes of Cerebral Cortex in Embryonic 18 Days

Project description:Cajal-Retzius cells have important role in cerebral cortex development, such as secreted Reln protein, maintain normal lays of cerebral cortex. To explore novel secretory protein of Cajal-Retzius cells and to survey the roles of Cajal-Retzius cells in cerebral cortex development, we analyzed transcriptome profiles of 6753 single cells of the embryonic 18 days.

2019-11-27 | GSE123035 | GEO

11 week Niemann-Pick type C1 Mouse Cerebellum and Cerebral Cortex Proteomics

Project description:Label-free quantification of cerebellum and cerebral cortex proteomics in 11 week wild type and NPC1 null mice

2018-02-08 | MSV000082040 | MassIVE

Single-cell RNA-seq of mouse cerebral cortex

2015-02-20 | GSE60361 | GEO

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

Project description:While the cerebral cortex is organized into six excitatory neuronal layers, it is unclear whether glial cells show distinct layering. Here, we developed a high-content pipeline, the Large-area Spatial Transcriptomic (LaST) map, which can quantify single-cell gene expression in situ. Screening 46 candidate genes for astrocyte diversity across the mouse cortex, we identified superficial, mid, and deep astrocyte identities in gradient layer patterns that were distinct from those of neurons. Astrocyte layer features, established in early postnatal cortex, mostly persisted in adult mouse and human cortex. Single cell RNA sequencing and spatial reconstruction analysis further confirmed the presence of astrocyte layers in the adult cortex. Satb2 and Reeler mutations that shifted neuronal post-mitotic development were sufficient to alter glial layering, indicating an instructive role for neuronal cues. Finally, astrocyte layer patterns diverged between mouse cortical regions. These findings indicate that excitatory neurons and astrocytes are organized into distinct lineage-associated laminae.

2020-07-15 | GSE140822 | GEO

11 week Niemann-Pick type c1 label-free mouse cerebellum and cerebral cortex proteomics

Project description:label-free quantification using 11 week mouse tissue lysates from cerebellum and cerebral cortex of wild type and NPC1 null mice.

2018-02-08 | MSV000082039 | MassIVE

Single cell RNA-seq for brain cerebral cortex transcriptome

Project description:Single cell RNA-seq for brain cerebral cortex transcriptome

| PRJNA649578 | ENA

Single cell RNA-seq for brain cerebral cortex transcriptome

Project description:Single cell RNA-seq for brain cerebral cortex transcriptome

| PRJNA810030 | ENA