Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Lactiplantibacillus plantarum strain:ATG-K8

ABSTRACT: Lactobacillus plantarum strain ATG-K8 genome sequencing and assembly

PROVIDER: PRJNA492154 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Lactiplantibacillus plantarum strain:ATG-K2

Project description:Lactobacillus plantarum strain ATG-K2 genome sequencing and assembly

| PRJNA492149 | ENA

Lactiplantibacillus plantarum strain:ATG-K6

Project description:Lactobacillus plantarum strain ATG-K6 genome sequencing and assembly

| PRJNA492151 | ENA

Lactiplantibacillus plantarum strain:ATG-K20

Project description:Lactiplantibacillus plantarum strain ATG-K20 chromosome, complete genome

| PRJNA1250170 | ENA

Lactiplantibacillus plantarum strain:ATG-V2

Project description:Lactiplantibacillus plantarum strain ATG-V2 chromosome, complete genome

| PRJNA1250167 | ENA

Lactiplantibacillus plantarum strain:ATG-V8

Project description:Lactiplantibacillus plantarum strain ATG-V8 chromosome, complete genome

| PRJNA1250169 | ENA

Transcriptome analyses of aggregating Lactiplantibacillus plantarum

Project description:The transcriptome of L. plantarum strains that aggregate was compared with non-aggregating strains

2021-04-20 | GSE172351 | GEO

Lactiplantibacillus plantarum

Project description:Lactobacillus plantarum LP3 Genome sequencing and assembly

| PRJNA340346 | ENA

Lactiplantibacillus plantarum K8 lysates regulate hypoxia-induced gene expression.

Project description:Hypoxic responses have been implicated in critical pathologies, including inflammation, immunity, and tumorigenesis. Recently, efforts to identify effective natural remedies and health supplements are increasing. Previous studies have reported that the cell lysates and the cell wall-bound lipoteichoic acids of Lactiplantibacillus plantarum K8 (K8) exert anti-inflammatory and immunomodulative effects. However, the effect of K8 on cellular hypoxic responses remains unknown. In this study, we found that K8 lysates had a potent suppressive effect on gene expression under hypoxia. K8 lysates markedly downregulated hypoxia-induced HIF1α accumulation in the human bone marrow and lung cancer cell lines, SH-SY5Y and H460. Consequently, the transcription of known HIF1α target genes, such as p21, GLUT1, and ALDOC, was notably suppressed in the K8 lysate supplement and purified lipoteichoic acids of K8, upon hypoxic induction. Intriguingly, K8 lysates decreased the expression of PHD2 and VHL proteins, which are responsible for HIF1α destabilization under normoxic conditions, suggesting that K8 may regulate HIF1α stability in a non-canonical pathway. Overall, our results suggest that K8 lysates desensitize the cells to hypoxic stresses and suppress HIF1α-mediated hypoxic gene activation.

| S-EPMC10943017 | biostudies-literature

Lactiplantibacillus plantarum

Project description:Lactobacillus plantarum Genome sequencing

| PRJNA392545 | ENA

Lactiplantibacillus plantarum

Project description:Lactobacillus plantarum Genome sequencing

| PRJNA352107 | ENA