Project description:To investigate the resistance mechanism of control drugs in resisting CMV virus, we established an indoor CMV- Passion fruit seedling in vivo screening model, treated with different antiviral commercial agents, and then we performed gene expression profiling on RNA-seq data of the best effective drug treatment group.
Project description:Passiflora mollissima commonly known as “banana passion fruit” is usually consumed as fresh food or processed products, being seeds and peel the main by-products of the industrial processing. The potentially bioactive metabolites from banana passion fruit PLE-extract seeds have been recently characterized by HPLC-HRMS after sequential pressurized liquid extraction (PLE) To apply a Foodomics approach to study the effects of a banana passion fruit seeds PLE-extract (with high antioxidant capacity and enriched in phenolic-type compounds) on the transcriptome and metabolome of HT-29 colon cancer cells.
Project description:This model was reconstructed from single-nucleus RNA-seq (snRNA-seq) data of human postmortem brain and curated using published metabolomics data from human iPSC-derived neurons and cerebrospinal fluid (CSF), together with gene expression data from the Human Protein Atlas. It more accurately simulates human neuronal metabolic flux in neurodegenerative conditions such as Alzheimer's disease (AD).
Project description:Using ChIP-seq to study the deposition of RIN in WT tomato AC fruits and pCBC::RIN-3xFLAG, pCBC::RIN-3xFLAG/dml2-3 tagline fruits at 34 dpa (Breaker stage)