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Next generation sequencing analysis of mRNA profile in cisplatin-resistant gastric cancer cell line SGC7901

ABSTRACT: Next generation sequencing analysis of mRNA profile in cisplatin-resistant gastric cancer cell line SGC7901

PROVIDER: PRJNA503804 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8156430.fastq.gz	Fastqsanger.gz
	SRR8156431.fastq.gz	Fastqsanger.gz

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Next generation sequencing analysis of mRNA profile in cisplatin-resistant gastric cancer cell line SGC7901

Project description:Cisplatin-resistant gastric cancer (GC) occurs in patients with GC treated with cisplatin-based chemotherapy, which results in disease progression and early recurrence during the treatment. To understand the initiation and developmental mechanism underlying cisplatin-resistant GC, we developed cisplatin resistant SGC7901 cells (SGC7901/DDP) from the parental cells (SGC7901/S) by continuous exposure to increasing concentrations of cisplatin and subjected these two cell lines to RNA sequencing analysis.

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