Project description:We performed RNA-sequencing of testes derived from Atr+/+ or Atr+/KD 7 weeks old mice. Since Atr+/KD male mice are sterile and present severe spermatogenesis defects, we aimed at analyzing the possible changes in gene expression given by the ATR kinase-dead (KD) mutation
Project description:Expression changes in testes of 5 week old mice after knockout of Phf13 were analyzed using Affymetrix mouse genome 430 2.0 expression microarrays. Transcripts on the X- and Y-chromosome were significantly upregulated.
Project description:Expression changes in testes of 15-20 week old mice after knockout of Phf13 were analyzed using Affymetrix mouse genome 430 2.0 expression microarrays. Transcripts on the X- and Y-chromosome were significantly upregulated.