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Genes regulated in HT-1080 cells after treatment with IRAK4 inhibitor

ABSTRACT: Genes regulated in HT-1080 cells after treatment with IRAK4 inhibitor

PROVIDER: PRJNA506896 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	SRR8239090.fastq.gz	Fastqsanger.gz
	SRR8239110.fastq.gz	Fastqsanger.gz
	SRR8239091.fastq.gz	Fastqsanger.gz
	SRR8239092.fastq.gz	Fastqsanger.gz
	SRR8239093.fastq.gz	Fastqsanger.gz

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Project description:Analysis of HT-1080 fibrosarcoma cells transcriptome following 24 hours treatment with IRAK4 inhibitor was performed. Results provide insight into mode of action of IRAK4 inhibitor under study. Project co-financed from European Regional Development Fund under The Operational Program Innovative Economy, 2007-2013, measure 1.4 (UDA-POIG.01.04.00-12-049/11-00)

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Genes regulated in HT-1080 cells after 24 hours of treatment with IRAK4 inhibitor

Project description:Genes regulated in HT-1080 cells after 24 hours of treatment with IRAK4 inhibitor

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RepliSeq of HT-1080 cell line

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Project description:Analysis of replication timing by RepliSeq of HT-1080 Human Connective Tissue Fibrosarcoma Cells. HT-1080 subclone +4 cell line as described in “Human gene targeting favors insertions over deletions.” Russell, D.W., and Hirata, R.K. (2008). Hum Gene Ther 19, 907-914. RepliSeq of HT-1080 cell line was used to determine the impact of DNA replication on targeted adeno-associated virus sites by mapping replication forks, which revealed a consistent preference for recombination at target loci transcribed towards an incoming fork.

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Proteomic analysis of HT-1080 cells overexpressing protein ARGLU1

Project description:A proteomic comparison between normal HT-1080 cells and HT-1080 cells that have been stably transfected to overexpress protein arginie and glutamate rich 1 (ARGLU1).

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Development of gene expression signatures for subconfluent and overconfluent HT-1080 fibrosarcoma cell line

Project description:We investigated the changes in gene expression profile between subconfluent (80%) and overconfluent HT-1080 fibrosarcoma cell line. We have employed whole genome microarray expression profiling as a discovery platform to identify genes expression profiles in HT-1080 cells. Total RNAs from subconfluent (HT-1080_80%) and overconfluent (HT-1080_overconfluent) HT-1080 cells were harvested and subjected to the microarray analysis.

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Genes regulated in HT-1080 cells after treatment with IRAK4 inhibitor

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