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ABSTRACT: Satellite DNA evolution in Characiformes

PROVIDER: PRJNA516575 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11676679_1.fastq.gz	Fastqsanger.gz
	SRR11676679_2.fastq.gz	Fastqsanger.gz
	SRR11676680_1.fastq.gz	Fastqsanger.gz
	SRR11676680_2.fastq.gz	Fastqsanger.gz
	SRR11676681_1.fastq.gz	Fastqsanger.gz

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Project description:We report the sequences bound to CENP-A in the dog genome (Canis familiaris) for high-throughput characterization of centromeric sequences. We compare these ChIPSeq reads (72 bp, single read) against a reference centromeric satellite DNA domain database for the dog genome, resulting in the annotation of sequence variation and estimated abundance of seven satellite families together with adjacent, non-satellite sequences. To study global patterns of sequence diversity and characterizing the subset of sequences correlated with centromere function, these sequences were evaluated relative to a comprehensive centromere sequence domain k-mer library. From this analysis, we identify functional sequence features from two satellite families (CarSat1 and CarSat2) that are defined by distinct arrays subtypes. Sequences bound to CENP-A in MDCK (dog) cell line

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