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Genome-wide maps of chromatin state in MDA-MB-231 cells [ChIP-seq]

ABSTRACT: Genome-wide maps of chromatin state in MDA-MB-231 cells [ChIP-seq]

PROVIDER: PRJNA526855 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8719700.fastq.gz	Fastqsanger.gz
	SRR8719701.fastq.gz	Fastqsanger.gz
	SRR8719702.fastq.gz	Fastqsanger.gz
	SRR8719703.fastq.gz	Fastqsanger.gz
	SRR8719704.fastq.gz	Fastqsanger.gz

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Project description:We report a series of ChIP-Seq results in MDA-MB-231 cells. Briefly, we performed ChIP-Seq experiments with antibodies specific for PHF20L1, MTA1, EZH2, H3K27me2, H3K27me3 and H3K27ac in normal or knockdown of PHF20L1 MDA-MB-231 cells . We found that knockdown of PHF20L1 reduced the enrichment of MTA1, EZH2, H3K27me2, and H3K27me3 on the PHF20L1 target gene, and the enrichment of H3K27ac increased. This study gave us a new understanding of the role of PHF20L1 in chromatin status and gene transcription.

2020-03-12 | GSE128231 | GEO

Expression profiles of MDA-MB-231, MDA-231 S1a and S1b

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