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Gene expression data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells [48 hours]

ABSTRACT: Gene expression data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells [48 hours]

PROVIDER: PRJNA528799 | ENA |

REPOSITORIES: ENA

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Gene expression data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells [48 hours]

Project description:To investigate the molecular mechanism of the hypopigmentation observed in Dicer KO mice, Dicer knockdown was realised in vitro in normal C57BL/6 mouse melanocyte Melan-a cells. Transient transfection of Melan-a cells with siRNA directed against Dicer reduced Dicer protein levels to approximately 40% of that of siScr Melan-a cells 48 hours after transfection. We analyzed the transcriptome of Melan-a cells 48 hours after transfection with siDicer or siScr to understand the molecular mechanisms involved in Dicer-dependent melanocyte migration.

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microRNA levels data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells

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Gene expression data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells [24 hours]

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Gene expression data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells [24 hours]

Project description:Gene expression data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells [24 hours]

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Melan-a cells expressing reduced level of Dicer and control Melan-a cells

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Project description:microRNA levels data from Melan-a cells expressing reduced level of Dicer and control Melan-a cells

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