Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Characterization of two MHC II genes (DOB, DRB) in white-tailed deer (Odocoileus virginianus)

PROVIDER: PRJNA533917 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8934360_1.fastq.gz	Fastqsanger.gz
	SRR8934360_2.fastq.gz	Fastqsanger.gz
	SRR8934370_1.fastq.gz	Fastqsanger.gz
	SRR8934370_2.fastq.gz	Fastqsanger.gz
	SRR8934380_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 760

Similar Datasets

Project description:Odocoileus virginianus (white-tailed deer) sequencing

| PRJNA578444 | ENA

Project description:RNA-seq of brain transcriptome from white-tailed deer (WTD Odocoileus virginianus)

| PRJNA756812 | ENA

Project description:Differential gene expression in chronic wasting disease infected white-tailed deer (Odocoileus virginianus)

| PRJNA487608 | ENA

Project description:Complete genome sequence of mobuck virus from a Florida white-tailed deer (Odocoileus virginianus)

| PRJNA506057 | ENA

Project description:Genome Sequence of Yunnan Orbivirus Isolated from a Florida White-Tailed Deer (Odocoileus virginianus)

| PRJNA689537 | ENA

Odocoileus virginianus WGS

Project description:Illumina paired end whole genome sequencing of an adult white-tailed deer Odocoileus virginianus

| PRJEB20034 | ENA

Identification of Amblyomma americanum antigens after vaccination with tick extracellular vesicles in white-tailed deer

Project description:Anti-tick vaccines represent a promising alternative to chemical acaricides for the management of ticks on wildlife; however little progress has been made to produce an effective vaccine in hosts relevant to tick reproduction. Further, most of the antigens described are expressed during feeding in domesticated hosts and may not activate the immune system in wild hosts. We recently tested Amblyomma americanum salivary (SG) and midgut (MG) extracellular vesicles (EVs) as vaccine candidates in white-tailed deer (Odocoileus virginianus; WTD), which resulted in on-host female tick mortality. Herein, we describe our efforts to identify the antigenic proteins found within these vesicles. Within both SG- and MG-EVs, an enriched “core- cargo” was identified within both SG- and MG-EVs, including chaperones, small GTPases, and other proteins previously reported in small EVs was discovered. Label-free quantitative proteomics showed significant differences in protein cargo between MG and SG-EVs (333 proteins out of 516). Serum from three vaccinated WTD (pre-vaccinated and day 57 post vaccination) and one control WTD was used to immunoprecipitated antigenic proteins from SG- and MG-EV preparations. Proteomic analysis of immunoprecipitated proteins identified seven antigenic proteins in SG-EVs and one in MG-EVs that were statistically significantly different from the pre-vaccinated serum. Moreover, these proteins were unique to vaccinated animals (not precipitated by control serums). Additionally, two MG-EVs and 24 SG-EV proteins show antigenic potential. These proteins represent promising candidates for anti-tick vaccine design in WTD and other wildlife.

2025-05-26 | PXD058874 | Pride

Project description:Metagenomic sequencing sheds light on microbes putatively associated with pneumonia-related fatalities of white-tailed deer (Odocoileus virginianus)

| PRJNA1025254 | ENA

Project description:Alterations in gut microbiota linked to provenance, sex, and chronic wasting disease in white-tailed deer (Odocoileus virginianus)

| PRJNA688284 | ENA

Project description:Epidemiology, Genome Features, and Antimicrobial Resistance of Trueperella pyogenes Isolated from Farmed White-tailed Deer (Odocoileus virginianus) in Florida

| PRJNA1338263 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data