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ABSTRACT: Evolution of gallium resistance in Pseudomonas aeruginosa

PROVIDER: PRJNA540579 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12102906_1.fastq.gz	Fastqsanger.gz
	SRR12102906_2.fastq.gz	Fastqsanger.gz
	SRR12102907_1.fastq.gz	Fastqsanger.gz
	SRR12102907_2.fastq.gz	Fastqsanger.gz
	SRR12102908_1.fastq.gz	Fastqsanger.gz

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Whole-genome resequencing of Pseudomonas aeruginosa PAO1 after anti-virulence treatments targeting iron uptake

Project description:We carried out an experimental evolution in human serum as an ex-vivo model and screened evolved lines for the evolution of resistance phenotypes towards two anti-virulence treatments, gallium and flucytosine, which both target the iron scavenging pyoverdine of Pseudomonas aeruginosa (each at 2 different doses). We performed whole-genome sequencing of 16 evolved clones from the different treatment regimes .

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