Project description:Using microarray analyses and subsequent verification by RT-PCR, we studied the changes in gene expression in the inferior colliculus after an ictal event in one models of audiogenic epilepsy, Wistar audigenic rat (WAR). WAR is a genetically selected strain susceptible to audiogenic seizures that was inbred in the School of Medicine of Ribeirão Preto (Brazil) beginning in 1990. This strain is a model of audiogenic idiopathic epilepsy that develops tonic-clonic generalized seizures. Genetic animal models of epilepsy are an important tool for further understanding the basic cellular mechanisms underlying epileptogenesis and for developing novel antiepileptic drugs. We conducted a comparative study of gene expression in the inferior colliculus, a nucleus that triggers audiogenic seizures, using two animal models, the Wistar audiogenic rat (WAR) and the genetic audiogenic seizure hamster (GASH:Sal). For this purpose, both models were subjected to auditory stimulation, and 60 minutes after stimulation, the inferior colliculi were collected. As a control, intact Wistar rats and Syrian hamsters were subjected to identical stimulation and tissue preparation protocols to those performed on the experimental animals.
2015-12-31 | GSE74150 | GEO
Project description:Genome sequencing of 34 clinical isolates from a university hospital in Ribeirao Preto, SP, Brazil
| PRJNA641571 | ENA
Project description:Sequencing of the complete genome of a new virus Rio Preto Tick Virus belonging to the Jingmenvirus group
Project description:Fungus gardens microbial communities from leaf cutter ant in Ribeirão Preto, State of São Paulo, Brazil - Atta sexdens ASBM3 metagenome
Project description:Fungus gardens microbial communities from leaf cutter ant in Ribeirão Preto, State of São Paulo, Brazil - Atta laevigata ALBM1 metagenome
Project description:Fungus gardens microbial communities from leaf cutter ant in Ribeirão Preto, State of São Paulo, Brazil - Atta laevigata ALBM2 metagenome
Project description:Fungus gardens microbial communities from leaf cutter ant in Ribeirão Preto, State of São Paulo, Brazil - Atta laevigata ALBM3 metagenome
Project description:Fungus gardens microbial communities from leaf cutter ant in Ribeirão Preto, State of São Paulo, Brazil - Atta sexdens ASBM2 metagenome