Project description:<p>This is a study of the oral and gut microbiome of 226 mother-child dyads enrolled in the INSIGHT (Intervention Nurses Start Infants Growing on Healthy Trajectories) study. INSIGHT is a randomized, controlled trial comparing a responsive parenting intervention designed for the primary prevention of childhood obesity against a control. </p> <p>The microbiome portion of the study was designed to investigate the relationship between a cross-sectional view of the child's microbiome (at two years of age) and the patterns of growth between birth and 2 years. These first-born children were deeply studied in this time period with data collected on a wide variety of variables including mode of delivery, sex, weight and height (collected at 7 time points), medication usage, diet information, and maternal health information (gestational weight gain, gestational diabetes, smoking during pregnancy). Microbiome samples from the child (buccal swab and stool sample) and their mother (buccal swab) were collected at the child's 2-year clinical research visit. </p>
Project description:The present study uses an intra-familial design, matching affected and unaffected sibling pairs by sex and age and controlling for pharmacological treatment in the autistic sibling. The aim of this study is to find ASD blood biomarkers possibly applicable within “high risk” families, where one child has already received an ASD diagnosis.
2023-02-05 | GSE212645 | GEO
Project description:Fecal microbiome of mother-infant pairs
| PRJNA1147875 | ENA
Project description:Fecal microbiome of mother-infant pairs
Project description:This study is being conducted to learn more about family communication of genetic risk information. Semi-structured interviews lasting up to one hour will be conducted with three populations: parent/child pairs at risk for Huntington’s Disease, parent/child pairs at risk for hereditary cancer, and genetic counselors.
| 2264963 | ecrin-mdr-crc
Project description:Vaginal microbiome of reproductive age mother daughter pairs
| PRJNA779415 | ENA
Project description:Neonatal Gut Microbiome in a mother child paired design
Project description:The objective of the present study was to identify the nutrient utilization and the SCFA production potential of gut microbes during the first year of life. The 16S sequencing data represents 100 mother-child pairs, longitudinally for the infants (0, 3mo, 6mo and 12mo) and mothers 18 weeks pregnancy. We wanted to identify the SCFA composition in pregnant woman and their infants through the first year of life, and their correlation to gut bacteria and other influencal factors. Metaproteomics on selected infants were analyzed to look for nutrient sources used by potential SCFA producers.
2021-09-09 | PXD017844 | Pride
Project description:16S rRNA sequences of human fecal microbiota of mother-child pairs from Southern Brazil