Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Comparison of WT and JNK3 KO (MAPK10-/-) gene expression in gastrocnemius muscle after hindlimb ischemia (HLI)

ABSTRACT: Comparison of WT and JNK3 KO (MAPK10-/-) gene expression in gastrocnemius muscle after hindlimb ischemia (HLI)

PROVIDER: PRJNA560286 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

GMP after hindlimb ischemia

Project description:GMP after hindlimb ischemia

| PRJNA746955 | ENA

Comparison of WT and JNK3 KO (MAPK10-/-) gene expression in gastrocnemius muscle after hindlimb ischemia (HLI)

Project description:JNK3 deficiency leads to upregulation of growth factors such as Vegfa, Pdgfb, Pgf, Hbegf and Tgfb3 in ischemic muscle. In order to ascertain the molecular mechanisms responsible for the accelerated blood flow recovery in Mapk10-deficient mice, a micro-array analysis of gastrocnemius muscle from these mice was performed after HLI. We observed a significant up-regulation of several growth factors known to improve blood flow recovery in the Mapk10-/- muscle compared to WT

2019-08-15 | GSE135853 | GEO

GMP after hindlimb ischemia

Project description:We perfomed RNA seq on GMP isolated from mice with sham (control) and hindlimb ischemia (HI) surgery.

2023-05-31 | GSE180171 | GEO

Transcription profiling of mouse extraocular and hindlimb muscle to determine gene expression changes in extraocular and hindlimb (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal day 56

Project description:Determination of gene expression changes in extraocular and hindlimb (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal day 56. 5 independent replicates/muscle group/strain.

2007-10-09 | E-GEOD-1472 | biostudies-arrayexpress

A novel model of chronic limb ischemia with translational significance enables proper evaluation of therapeutic angiogenesis

Project description:We aimed to develop a novel chronic and severe hindlimb ischemia mice model to properly evaluate the therapeutic effects of drug candidates in translational research for critical limb ischemia treatments. We used microarray to compare the gene expression patterns of gastrocnemius muscles at 1st week and 9th week after hindlimb ischemia model operation.

2020-06-10 | GSE152139 | GEO

Hindlimb muscle, comparison of wild type and mdx mice, 7 to 112 Day (Porter lab)

Project description:Determination of gene expression changes in hindlimb muscle (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal ages 7, 14, 23, 28, 56, and 112. Keywords: time-course

2004-02-10 | GSE1025 | GEO

Extraocular and hindlimb muscle, comparison of wild type and mdx mice, 56 days (Porter lab)

2004-06-15 | GSE1472 | GEO

Extraocular, masticatory, and hindlimb muscles, comparison of putative muscle allotypes (Porter lab)

Project description:Extraocular Muscle is Defined by a Fundamentally Distinct Gene Expression Profile. Adult mouse extraocular, masticatory, and hindlimb (gastrocnemius/soleus) muscles of adult mice were compared using Affymetrix microarrays. Data form part of publication: Proceedings of the National Academy of Sciences USA 98:12062-12067, 2001. Keywords: parallel sample

2004-02-27 | GSE1062 | GEO

Transcription profiling of mouse hindlimb muscle, comparison of wild type and mdx mice, 7 to 112 Day

Project description:Determination of gene expression changes in hindlimb muscle (gastrocnemius/soleus) of mdx (dystrophin-deficient) mice at postnatal ages 7, 14, 23, 28, 56, and 112.

2007-10-05 | E-GEOD-1025 | biostudies-arrayexpress

Hypoxia-induced miR-210 modulates gene expression in response to acute peripheral ischemia.

Project description:Peripheral Artery Disease is caused by the restriction or occlusion of arteries supplying the leg. Better understanding of the molecular mechanisms underpinning tissue response to acute and chronic ischemia is urgently needed to improve therapeutic options. The aim of this study is understanding miR-210 regulation and role in a mouse model of hindlimb ischemia. To investigate miR-210 function, mice were injected with a miR-210 complementary LNA-oligonucleotide (anti-miR-210). Then, the left femoral artery was dissected in order to induce unilateral hindlimb ischemia. Mice were sacrified 3 days later and gene expression profiles of gastrocnemius muscles were obatained.

2015-10-23 | E-GEOD-43340 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data