Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Eonycteris spelaea

ABSTRACT: Eonycteris spelaea Metagenome

PROVIDER: PRJNA561193 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10179400_1.fastq.gz	Fastqsanger.gz
	SRR10179400_2.fastq.gz	Fastqsanger.gz
	SRR10179500_1.fastq.gz	Fastqsanger.gz
	SRR10179500_2.fastq.gz	Fastqsanger.gz
	SRR10179600_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 669

Similar Datasets

Eonycteris spelaea

Project description:Eonycteris spelaea overview

| PRJNA606370 | ENA

Heat stress response in the cave nectar bat Eonycteris spelaea differs from that of Mus musculus

Project description:Bats as the only flying mammals incur a high metabolic cost during extended powered flight, which results in febrile-like temperatures without injury. Herein, we investigate the in vivo heat shock response (HSR) in the cave nectar bat Eonycteris spelaea. We demonstrate that E. spelaea exhibits enhanced physiological heat resistance, marked by reduced lethality, tissue damage and serum corticosterone levels in comparison to mice upon heat challenge. Additionally, E. spelaea did not exhibit an acute transcriptional response observed heat stress in mice. Instead, bats displayed a delayed and non-canonical HSR that did not involve the activation of classical heat shock related genes and pathways. This altered response in E. spelaea is attributed to the elevated basal expression of heat shock proteins, which we demonstrate to be a common characteristic exhibited by bats from diverse sub-orders, families and diets. Taken together, we demonstrate a distinct HSR in E. spelaea relative to the conventional model organism, mouse, which may provide insights to understand novel regulatory targets and effector proteins that underlie the mammalian heat shock response.

2025-04-02 | GSE261939 | GEO

Eonycteris spelaea isolate:SIG01

Project description:Exploring the genome and transcriptome of the lesser dawn bat Eonycteris Spelaea with Pacbio long-read sequencing

| PRJNA427241 | ENA

Transcriptomic profiling of bat immune responses (e. spelaea)

Project description:To examine the fundamental immunity in bats, particularly the status of their innate immune system in the basal healthy state, we profile Eonycteris spelaea bat tissue with Deep NGS coverage. This is coupled to a paired experiment where bats were stimulated in vivo with various PRR ligands to activate immune pathways.

2020-02-12 | GSE129199 | GEO

Amblyopsis spelaea

Project description:Amblyopsis spelaea

| PRJNA737771 | ENA

Heat stress response in the cave nectar bat Eonycteris spelaea differs from that of Mus musculus

Project description:Heat stress response in the cave nectar bat Eonycteris spelaea differs from that of Mus musculus

| PRJNA1089609 | ENA

Amblyopsis spelaea

Project description:Amblyopsis spelaea overview

| PRJNA1191114 | ENA

Bat metagenome

Project description:Diet of Eonycteris spelaea

| PRJNA407714 | ENA

Immunophenotyping monocytes, macrophages and granulocytes in the Pteropodid bat Eonycteris spelaea.

Project description:Bats are asymptomatic reservoir hosts for several highly pathogenic viruses. Understanding this enigmatic relationship between bats and emerging zoonotic viruses requires tools and approaches which enable the comparative study of bat immune cell populations and their functions. We show that bat genomes have a conservation of immune marker genes which delineate phagocyte populations in humans, while lacking key mouse surface markers such as Ly6C and Ly6G. Cross-reactive antibodies against CD44, CD11b, CD14, MHC II, and CD206 were multiplexed to characterize circulating monocytes, granulocytes, bone-marrow derived macrophages (BMDMs) and lung alveolar macrophages (AMs) in the cave nectar bat Eonycteris spelaea. Transcriptional profiling of bat monocytes and BMDMs identified additional markers - including MARCO, CD68, CD163, CD172α, and CD88 - which can be used to further characterize bat myeloid populations. Bat cells often resembled their human counterparts when comparing immune parameters that are divergent between humans and mice, such as the expression patterns of certain immune cell markers. A genome-wide comparison of immune-related genes also revealed a much closer phylogenetic relationship between bats and humans compared to rodents. Taken together, this study provides a set of tools and a comparative framework which will be important for unravelling viral disease tolerance mechanisms in bats.

| S-EPMC6962400 | biostudies-literature

Panthera spelaea

Project description:Panthera spelaea Raw sequence reads

| PRJNA322637 | ENA