Gene expression profiling of dynamic paracrine senescence in human fibroblasts
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA580255 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR10360330.fastq.gz | Fastqsanger.gz | |||
| SRR10360331.fastq.gz | Fastqsanger.gz | |||
| SRR10360332.fastq.gz | Fastqsanger.gz | |||
| SRR10360333.fastq.gz | Fastqsanger.gz | |||
| SRR10360334.fastq.gz | Fastqsanger.gz |
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Project description:Senescence can be transmitted in a paracrine way from cells undergoing Oncogene Induced Senescence (OIS) to naïve normal cells. We define this phenomenon as “paracrine senescence” We used microarrays to compare the trancriptome of cells undergoing paracrine senescence to the transcriptome of cells suffering OIS to unveil the common signatures defining both events and the similarities between them
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