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A single cell transcriptome atlas of the developing zebrafish hindbrain [Fgf20a]

ABSTRACT: A single cell transcriptome atlas of the developing zebrafish hindbrain [Fgf20a]

PROVIDER: PRJNA593444 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10586527_1.fastq.gz	Fastqsanger.gz
	SRR10586527_2.fastq.gz	Fastqsanger.gz
	SRR10586528_1.fastq.gz	Fastqsanger.gz
	SRR10586528_2.fastq.gz	Fastqsanger.gz
	SRR10586529_1.fastq.gz	Fastqsanger.gz

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Project description:Purpose: The goal of this study is to understand the progressive patterning of neurogenesis of the developing zebrafish hindbrain. 16hpf, 24hpf and 44hpf zebrafish hindbrains were used for single-cell RNA-sequencing with the aim to uncover hindbrain development. Methods: 40 microdissected hindbrains per each stage were dissociated at loaded into the 10x Genomics Chromium Platform, and sequenced using Illumina HiSeq 4000. Conclusions: Our study constitute a resource of hindbrain gene expression during development. We have identified transcriptional programs involved in: rhombomere segmental identity, dorso-ventral patterning, boundary and centre progenitor cells and temporal regulation of neurogenesis.

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Project description:identification of differentially expressed genes in gas6 homozygous mutant hindbrain when compared to wildtype hindbrain in zebrafish

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A single cell transcriptome atlas of the developing zebrafish hindbrain

Project description:This SuperSeries is composed of the SubSeries listed below.

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