Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Differential gene expression in Hep3B and Hep3B SOX4-/- cells

ABSTRACT: Differential gene expression in Hep3B and Hep3B SOX4-/- cells

PROVIDER: PRJNA595153 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Differential gene expression in Hep3B and Hep3B SOX4-/- cells

Project description:Overexpression of SOX4 in various kinds of cancers specimen was associated with poor prognosis of patients; however, the role of SOX4 in angiogenesis or tumor microenvironment modulation remains unclear. Therefore the endogenous SOX4 was knockout and the differential gene expression between Hep3B and Hep3B SOX4-/- cells were examined via genechip. We found that the differentially expressed genes, EzH2, a SOX4-associated partner, and CXCL12, were repressed in Hep3B SOX4-/- cells compared with parental Hep3B; these results were further assessed via qRT-PCR in Hep3B SOX4-/- versus Hep3B cells.

2020-12-01 | GSE141909 | GEO

Differential expression profiles of RNAs in Hep3B cells treated with Bufotalin

Project description:Differential expression profiles of RNAs in Hep3B cells treated with Bufotalin

| PRJNA1143374 | ENA

Differential expression profiles of RNAs in Hep3B cells after silencing LINC01547

Project description:Differential expression profiles of RNAs in Hep3B cells after silencing LINC01547

| PRJNA1143373 | ENA

Differential expression profiles of RNAs in Hep3B cells after silencing LINC01547

Project description:We extracted the total RNA of Hep3B cells after silencing LINC01547 for 48 h and used RNA-seq technology to detect differentially expressed RNAs in Hep3B cells.

2025-08-10 | GSE273802 | GEO

Differential expression profiles of RNAs in Hep3B cells treated with Bufotalin

Project description:We extracted the total RNA of Hep3B cells treated with Bufotalin for 48 h and used RNA-seq technology to detect differentially expressed RNAs such as lncRNAs, miRNAs, and mRNAs in Hep3B cells.

2025-08-10 | GSE273801 | GEO

Differential mRNA expression profile regulated by HNF4α in Hep3B cells

Project description:A previous study from this laboratory demonstrated that up-regulating HNF4a could reverse the malignant phenotypes of HCC by inducing redifferentiation of HCC cells to hepatocytes. To study the mechanisms of the hepatic differentiation effect by HNF4α, we used the cDNA microarray to detect differential gene expression profiles of Hep3B infected with AdHNF4α and AdGFP. Expression profile analysis revealed that HNF4α positively regulated 1218 mRNAs and negatively regulated 1411 mRNAs for more than 2 times. The pathway analysis for the differential genes showed that the genes were involved in Complement and coagulation cascades, metabolism, Type II diabetes mellitus, Pathways in cancer etc.

2015-06-01 | GSE66785 | GEO

Gene expression profiling of Nedd4- or control-knockdown Hep3B cells

Project description:Gene expression profiling of Nedd4 or control knockdown Hep3B cells

2017-06-12 | GSE66341 | GEO

Gene expression profiling of control and AMPK knockdown Hep3B cells

Project description:Gene expression profiling of control and AMPK knockdown Hep3B cells

2022-03-26 | GSE97155 | GEO

RNA-Seq in Hep3B-shNC and Hep3B-shlnc-CTHCC cells

Project description:RNA-Seq in Hep3B-shNC and Hep3B-shlnc-CTHCC cells

| PRJNA674827 | ENA

Effect of hypoxia on gene expression in Hep3B cells

Project description:Effect of hypoxia on gene expression in Hep3B cells