Project description:To explore the role of circRNAs during ILC3-driven colitis, we isolated ILC3s from DSS treated or control Rag1-/- mice. Then circRNA microArray analysis were performed and differentially expressed circRNAs were identified.
Project description:To explore the role of circRNAs during CRC (colorectal cancer) metastasis, we isolated CRC cells from human sample and performed transwell assay. Then circRNA microArray analysis were performed and differentially expressed circRNAs were identified.
Project description:Purpose: To detect RNA-seq of NKp44- ILC3s and NKp44+ ILC3s in lung cancer and find the differences between these tow group. Results:Compared with those of NKp44+ILC3s, NKp44-ILC3s had 12,965 DEGs, with 6161 up-regulated genes and 6804 down-regulated genes,most DEGs related to the functions of cellular process, biological regulation, cell component, and molecular binding.
Project description:IL-17D/CD93 axis was essential for ILC3s hemostasis. In order to further understand how IL-17D-CD93 axis regulate ILC3s function, we conducted RNA-seq analysis of ILC3s.
Project description:Analyses of ILC3s in Rorc floxed control and Id2iÎ?RORγt mice following daily treatments of tamoxifen for two weeks. Cells were sort purified as lineage negative, CD127+ CD90.2+ CCR6+ ST2- CCR6+ ILCs were sorted from the mesenteric LN of Rorc floxed control and Id2iÎ?RORγt mice following daily treatments of tamoxifen for two weeks.