Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The G-protein coupled receptor GPR8 regulates secondary metabolism and mating associated chemical communication in Trichoderma reesei

ABSTRACT: The G-protein coupled receptor GPR8 regulates secondary metabolism and mating associated chemical communication in Trichoderma reesei

PROVIDER: PRJNA603960 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10989748.fastq.gz	Fastqsanger.gz
	SRR10989749.fastq.gz	Fastqsanger.gz
	SRR10989750.fastq.gz	Fastqsanger.gz
	SRR10989751.fastq.gz	Fastqsanger.gz
	SRR10989752.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 14

Similar Datasets

The G-protein coupled receptor GPR8 regulates secondary metabolism and mating associated chemical communication in Trichoderma reesei

Project description:GPR8 exerts a light dependent function on secondary metabolism, which is in part mediated by YPR2 and the function of SOR7

2020-01-31 | GSE144529 | GEO

A G-protein coupled receptor supports methionine response in Trichoderma reesei

Project description:We investigated the function of the G-protein coupled receptor 72004 in Trichoderma reesei and found that it is involved in methionine response and gene expression in light and darkness

2024-01-01 | GSE222724 | GEO

A G-protein coupled receptor supports methionine response in Trichoderma reesei

Project description:A G-protein coupled receptor supports methionine response in Trichoderma reesei

| PRJNA923275 | ENA

Trichoderma reesei Nsd3 transcription factor: pleiotropic roles in development, stress response, secondary metabolism, and cellulase production

Project description:Trichoderma reesei is widely known for its ability to secrete high amounts of cellulases, enzymes of fundamental importance in generating products from lignocellulosic biomass. Diverse signaling pathways and transcription factors (TFs) control the cellulolytic repertoire in T. reesei to ensure correct adaptation to the environment and consumption of the most favorable carbon source. Here, we analyzed RNA-Seq data and identified a new potential regulator of cellulase production in T. reesei: a novel zinc finger TF named Nsd3, homolog of NsdC from Aspergilli. Deletion of nsd3 reduced vegetative growth and conidiation on solid medium. Phenotypic characterization of the Δnsd3 strain showed that it is more sensitive to osmotic stress but more resistant to cell wall and oxidative stresses. Our results showed that Nsd3 acts as a repressor of cellulase expression, an unreported role for this TF in fungi. Loss of nsd3 leads to a faster and more robust induction of cellulolytic genes and higher cellulase and hemicellulase activities. Transcriptional profiling by RNA-Seq and chromatin accessibility profiling by ATAC-Seq showed that sugar transporters are important targets of Nsd3 during cellulase expression regulation. Combined with microscopy and gene expression analyses, the ATAC-Seq data also highlighted Nsd3 as a central regulator of cell wall remodeling and organization. Furthermore, the transcriptomics also showed that Nsd3 regulates genes involved in secondary metabolism. These results showed that Nsd3 regulates several physiological processes and provide novel insights into the regulatory system of cellulases in T. reesei that can be used in the design of high-performance strains for biorefinery.

2026-05-31 | GSE328452 | GEO

Trichoderma reesei Nsd3 transcription factor: pleiotropic roles in development, stress response, secondary metabolism, and cellulase production [ATAC-seq]

2026-05-31 | GSE327621 | GEO

Transcriptome analysis of T. reesei CBS999.97, backcrossed female fertile strains in QM6a genetic background and QM6a upon mating

Project description:The aim of this study was to evaluate changes in the transcriptome in the mentioned strains during mating conditions

2017-11-07 | GSE89104 | GEO

The MAPKinase TMK3 in Trichoderma reesei

Project description:We investigated the functions of the HOG pathway MAPKinase tmk3 = TR_45018 in Trichoderma reesei

2025-12-31 | GSE236209 | GEO

The role of pheromone receptors for communication and mating in Hypocrea jecorina (Trichoderma reesei).

Project description: Not available

| S-EPMC3462998 | biostudies-literature

The HOG pathway MAPKKK TR_57513 in Trichoderma reesei

Project description:We investigated the functions of the MAPKKK (TR_57513) from the HOG pathway in Trichoderma reesei

2025-12-31 | GSE236210 | GEO

Trichoderma reesei QM6a CGH self hybridization

Project description:We perform a self hybridisation comprative genomic hybridization (CGH) in order to validate the probe tiling design we done on Trichoderma reesei. This hybridization was done using QM6a wild type strain.

2010-03-16 | GSE17752 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data