Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: macaque ICD rectal swabs cases vs controls

PROVIDER: PRJNA608547 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11176600_1.fastq.gz	Fastqsanger.gz
	SRR11176600_2.fastq.gz	Fastqsanger.gz
	SRR11176601_1.fastq.gz	Fastqsanger.gz
	SRR11176601_2.fastq.gz	Fastqsanger.gz
	SRR11176602_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 186

Similar Datasets

Homo sapiens

Project description:Human rectal adenoma (8 cases) vs. rectal carcinoma (8 cases)

| PRJNA151349 | ENA

Human gut microbiota, COVID-19 patients with mild or severe symptoms.

Project description:Analysis of COVID-19 hospitalized patients, with different kind of symptoms, by human rectal swabs collection and 16S sequencing approach.

2022-09-22 | E-MTAB-12236 | biostudies-arrayexpress

Metatranscriptomics of the macaque juvenile gut microbiome in health and chronic diarrhea

Project description:Background: Idiopathic Chronic Diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. Characterized by chronic inflammation of the colon and repeated bouts of diarrhea, ICD is largely unresponsive to medical interventions including corticosteroid, antiparasitic and antibiotic treatments. Although ICD is accompanied by large disruptions in the composition of the commensal gut microbiome, no single pathogen has been concretely identified as responsible for the onset and continuation of the disease. Results: Fecal samples were collected from twelve ICD-diagnosed macaques and twelve age and sex-matched controls. RNA was extracted for metatranscriptomic analysis of species and activity within the gut microbiome. Using SAMSA2, these samples were contrasted to identify shifts both in overall organism activity and functional activity. Bacterial, fungal, archaeal, protozoan, and macaque (host) transcripts were simultaneously assessed. ICD-afflicted animals were characterized by increased activity of known bacterial pathogens and by decreased activity of archaeal methanogens. Interestingly, known fungal opportunists were not increased in ICD, nor were the usual enteric protozoans, although Trichomonas activity is up-regualted. Known mucin degrading organisms and mucin-degrading enzymes were up-regulated in the fecal microbiomes of ICD-afflicted animals. Assessment of colon sections using immunohistochemistry confirmed differential mucin composition between healthy control and ICD animals. Finally, assessment of host-derived transcripts confirms colonic inflammation and suggests that the lumen is infiltrated by granulocytes. Conclusions: The simultaneous profiling of bacterial, fungal, archaeal, protozoan, and macaque transcripts from stool samples suggests that ICD of rhesus macaques is associated with increased pathogen activity and altered mucin degradation.

2019-03-09 | GSE108572 | GEO

MK-swab-project-revision-data-11-22-2021-add-description-MK-McCall

Project description:Spotted 10uM of phenylacetylglutamine on a metal surface and used wooden cotton swabs to wipe the area after 45min. Extracted the recovery in Eppendorfs through centrifugation. Dried and resuspended the samples in 50% methanol spiked with sulphadimethoxine for LC-MS analysis. Spotted samples were wiped for 1min vs 5sec, once vs twice, and the cotton swab rinsed in some cases. Data file names in the master sequence and Skyline report are labeled as "car-XX.raw", but in all cases the standard is actually phenylacetylglutamine.

2021-12-04 | MSV000088511 | MassIVE

Project description:mNGS of North American bat rectal swabs

| PRJNA1276114 | ENA

Homo sapiens

Project description:Large rare Deletions in Ashkenazi Jewish schizophrenia cases vs controls

| PRJNA131535 | ENA

Human rectal adenoma (8 cases) vs. rectal carcinoma (8 cases)

Project description:Genomic profiling of human rectal adenoma and carcinoma by array-based comparative genomic hybridization Two group experiment, rectal adenoma vs. rectal carcinoma. Biological replicates: 8 adenomas vs. 8 carcinomas

2011-12-20 | E-GEOD-34472 | biostudies-arrayexpress

Callithrix jacchus

Project description:Callithrix jacchus Metagenome of fecal and rectal swabs

| PRJNA508775 | ENA

Influenzavirus serotype association to global whole blood transcriptional changes

Project description:Febrile patients PCR positive for H1N1 swine flu, seasonal H1N1 and seasonal H3N2 in nasal swabs and controls consisting of febrile patients with rhinovirus infection or febrile patients of non-viral etiology (nasal swabs PCR negative for common respiratory viruses and blood PCR negative for dengue and parvovirus B19) were assessed consecutively for global transcriptional changes in whole blood

2014-04-01 | GSE29385 | GEO

Transcriptional profiling of irritant contact dermatitis (ICD) in a mouse model identifies specific patterns of gene expression and immune-regulation

Project description:Irritant contact dermatitis (ICD) is a non-immunological, cutaneous inflammatory response to a variety of triggers that requires no sensitization and accounts for up to 80% of occupational dermatitis cases. Numerous inflammatory cytokines play critical roles in the mechanism and severity of ICD, one being interleukin-6 (IL-6). Therefore, to investigate the influence of this pleotropic cytokine transcriptome analysis (MiSeq) was employed examining irritant-exposed and control skin samples from C57 and IL-6KO mice to gain a better understanding of the immunological mediators of ICD and what role IL-6 plays. Overall, this study offers new insight into the pathogenesis of ICD, indicates new mediators/markers that may influence the variability of responses to irritants and potential targets for therapeutic manipulation.

2018-09-04 | GSE95317 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data