Project description:To get insight of molecular effects of bEV on HEK293T cells, we investigated transcriptomic response in bEV treated HEK293T cells We identified differentially expressed genes (DEGs) fold change cutoff = 1.5 in the bEV treated HEK293T cells These findings suggest that bEV would be putative ingredients by modulating signaling pathways in human cells
Project description:In order to gain insight into the molecular mechanism of PROKR1, we investigated transcriptomic response in PROKR1 overexpressed HEK293 T cells following Pk2 stimulation We identified 578 differentially expressed genes (DEGs) fold change cutoff = 2 in activated HEK293 T overexpressed HEK293 T cells by Pk2, including 269 up-regulated and 309 down-regulated genes.
Project description:We present RNA-Seq data obtained from HEK293T cells and HEK293T cells with ALKBH5 and FTO demethylases double knockout (HEK293TΔALKBH5ΔFTO), showing m6A-dependent transcriptome alterations.