Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Caenorhabditis elegans strain:UA44

ABSTRACT: Caenorhabditis elegans strain:UA44 Genome sequencing

PROVIDER: PRJNA627736 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	SRR11808610_1.fastq.gz	Fastqsanger.gz
	SRR11808611_1.fastq.gz	Fastqsanger.gz
	SRR11808612_1.fastq.gz	Fastqsanger.gz
	SRR11808613_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 5

Similar Datasets

Caenorhabditis elegans founder strain mitochondrial UPR proteomics

Project description:This dataset consists of 20 proteomics raw files of two Caenorhabditis elegans strains: N2 and CB4856 under two conditions.

2021-12-28 | MSV000088622 | MassIVE

Infection of Pseudomonas donghuensis HYS strain and its fur deletion mutant in Caenorhabditis elegans

Project description:Infection of Pseudomonas donghuensis HYS strain and its fur deletion mutant in Caenorhabditis elegans was conducted to assess changes in the expression profile of Caenorhabditis elegans, and potential core virulence factors were identified by measuring the gene expression levels of the HYS colonizing the nematode's intestine. Preliminary studies indicate that P. donghuensis HYS exhibits significant toxicity towards Caenorhabditis elegans, yet the underlying mechanisms of this pronounced toxicity remain unclear. Previous work identified several virulence factors contributing to the toxicity of HYS through detection and functional validation; however, the molecular mechanisms responsible for its strong toxicity have not been elucidated. Therefore, we aim to analyze the mechanisms underlying HYS's pronounced toxicity by examining the responses of infected Caenorhabditis elegans. The Ferric uptake regulator (Fur) is responsible for maintaining iron homeostasis in Gram-negative bacteria, and given that HYS possesses a greater iron uptake capacity than other common species in the same genus, such as Pseudomonas aeruginosa, we hypothesize that Fur may play a critical role in the strong toxicity exhibited by HYS. Consequently, we infected Caenorhabditis elegans with both HYS and its fur deletion mutant and analyzed the changes in the expression profile of Caenorhabditis elegans. We observed a significant reduction in toxicity following the deletion of fur, indicating that Fur regulates core virulence factors. To identify these core virulence factors, we conducted transcriptomic sequencing of the pathogenic bacteria under various conditions and performed a screening for virulence factors.

2025-06-04 | GSE291743 | GEO

Caenorhabditis elegans strain:b261

Project description:Caenorhabditis elegans strain:b261 Genome sequencing

| PRJNA1305503 | ENA

Caenorhabditis elegans strain:N2

Project description:Caenorhabditis elegans strain:N2 Genome sequencing

| PRJNA225882 | ENA

Caenorhabditis elegans strain:N2

Project description:Caenorhabditis elegans strain:N2 Genome sequencing

| PRJNA223297 | ENA

Caenorhabditis elegans strain:N2

Project description:Caenorhabditis elegans strain:N2 Genome sequencing