Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Hainan upwelling marine column 18S rDNA data

ABSTRACT: Hainan upwelling marine column 18S rDNA data Raw sequence reads

PROVIDER: PRJNA628544 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11694859_1.fastq.gz	Fastqsanger.gz
	SRR11694859_2.fastq.gz	Fastqsanger.gz
	SRR11694860_1.fastq.gz	Fastqsanger.gz
	SRR11694860_2.fastq.gz	Fastqsanger.gz
	SRR11694861_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 60

Similar Datasets

marine upwelling 18S rDNA data

Project description:marine upwelling 18S rDNA data Raw sequence reads

| PRJNA628121 | ENA

marine upwelling 16S rDNA data

Project description:marine upwelling 16S rDNA data Raw sequence reads

| PRJNA639019 | ENA

18S rDNA

Project description:18S rDNA Raw sequence reads of the China Coastal Current

| PRJNA506331 | ENA

NEREA 18S rDNA

Project description:18S rDNA amplicon sequencing of NEREA size-fractionated samples

| PRJEB74658 | ENA

16S and 18S rDNA samples

Project description:16S and 18S rDNA samples Metagenome

| PRJNA548125 | ENA

18S rDNA from Sarcocystis rileyi in ducks

Project description:18S rDNA sequences from Sarcocystis rileyi which infect ducks

| PRJEB25732 | ENA

18S rDNA V4 region of environmental samples

Project description:18S rDNA V4 region of environmental samples Raw sequence reads

| PRJNA910243 | ENA

Visualize and quantify rDNA instabilities in mammalian cells and mouse models

Project description:Ribosomal DNA (rDNA) encodes the 18S, 5.8S, and 28S RNA components of ribosomes, accounting for up to 70% of cellular transcription. Despite its central role in cellular function and known association with cancer and aging, quantifying rDNA instability in mammals remains challenging due to its repetitive organization and inherent heterogeneity. In this study, we developed murine rDNA FISH probes and genomic tools tailored for laboratory strains. The results confirmed the locations of rDNA clusters, uncovered marked inter-/intra-strain and inter-cell heterogeneity at rDNA loci in inbred mice and unstressed cells, and identified sources of spontaneous, replication-associated DNA double-strand breaks within rDNA. Focused mini-screens using DNA repair-deficient cells uncovered distinct contributions of homologous recombination, non-homologous end-joining, and the ATM-mediated DNA damage response in safeguarding rDNA stability. Together, these findings and tools provide a robust framework for assessing rDNA instability in mammalian cells and animal models with applications in aging and cancer research.

2025-12-18 | GSE297694 | GEO

Visualize and quantify rDNA instabilities in mammalian cells and mouse models

Project description:Ribosomal DNA (rDNA) encodes the 18S, 5.8S, and 28S RNA components of ribosomes, accounting for up to 70% of cellular transcription activities. Despite its central role in cellular function and known association with cancer and aging, quantifying rDNA instability in mammals remains challenging due to its repetitive organization and inherent heterogeneity. In this study, we developed murine rDNA FISH probes and genomic tools tailored for laboratory strains. The results confirmed the locations of rDNA clusters, uncovered marked inter-/intra-strain and inter-cell heterogeneity at rDNA loci in inbred mice and unstressed cells, and identified sources of spontaneous, replication-associated DNA double-strand breaks within rDNA. Focused mini-screens using DNA repair-deficient cells uncovered distinct contributions of homologous recombination, non-homologous end-joining, and the ATM-mediated DNA damage response in safeguarding rDNA stability. Together, these findings and tools provide a robust framework for assessing rDNA instability in mammalian cells and animal models with utility in aging and cancer research.

2025-12-31 | GSE305294 | GEO

Araguaia River - 16S and 18S rDNA samples (project - 8 lakes)

Project description:Araguaia River - 16S and 18S rDNA samples (project - 8 lakes) Metagenome

| PRJNA629519 | ENA