Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gonadal white adipose tissue gene expression changes in response to adipose-specific Med19 knockout

ABSTRACT: Gonadal white adipose tissue gene expression changes in response to adipose-specific Med19 knockout

PROVIDER: PRJNA631658 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11767800.fastq.gz	Fastqsanger.gz
	SRR11767801.fastq.gz	Fastqsanger.gz
	SRR11767802.fastq.gz	Fastqsanger.gz
	SRR11767803.fastq.gz	Fastqsanger.gz
	SRR11767804.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 10

Similar Datasets

Gonadal white adipose tissue gene expression changes in response to adipose-specific Med19 knockout

Project description:We report the gene expression changes in the gWAT tissue of adipose-specific Med19 knockout mice

2020-08-01 | GSE150250 | GEO

Caveolin-1 knockout liver and gonadal adipose tissue

Project description:mRNA expression was compared in between wild type and caveolin-1 knockout livers mRNA expression was compared in between wild type and caveolin-1 knockout gonadal adipose tissue RNA was isolated from livers from male mice in at the light phase RNA was isolated from gonadal adipose tissues from male mice in at the light phase

2012-01-31 | E-GEOD-35431 | biostudies-arrayexpress

Caveolin-1 knockout liver and gonadal adipose tissue

2012-01-31 | GSE35431 | GEO

White adipose tissue from aP2-Pex5 knockout and control mice

Project description:These arrays contain data from gonodal adipose tissue of aP2-Pex5 -/- male mice 4 arrays from gonadal adipose tissue from control mice (Swiss background) are compared with 4 arrays from gonadal adipose tissue of aP2-Pex5 knockout mice. The latter lack functional peroxisomes in adipose tissue.

2012-03-01 | E-GEOD-31940 | biostudies-arrayexpress

Dose-dependent changes in gonadal white adipose tissue in TCDD-elicited steatohepatitis

Project description:Bulk RNA-sequencing of 27 C57BL/6 gonadal white adipose tissue samples where ovariectomized females were gavaged 4 days for 92 days with 0.01 to 30 µg/kg TCDD or sesame oil vehicle (n = 3) per dose.

2024-10-29 | GSE272683 | GEO

Transciptional profile analysis of the gonadal (peri-uterine) white adipose tissue of pregnant mice

Project description:In this study we performed RNA sequencing to determine the transcriptome of the gonadal white adipose tissue of pregnant wild type mice. We further assessed, using conditional RankΔFoxn1 knockout mice (which lack expression of Rank in the thymic epithelia), how the expression of the receptor Rank in the thymic medullary epithelia affects the transcriptional program of this tissue during pregnancy, and whether adoptive transfer of natural regulatory Tregs can rescue the alterations observed in the RankΔFoxn1 dams. For this study, we isolated at day E17.5 of pregnancy, the gonadal (peri-uterine) white adipose tissue of wildtype RankWt as well as of RankΔFoxn1 dams pregnant females that were treated at days E0.5-2.5 of pregnancy with either vehicle (PBS) or with 1x105 sorted-purified wild-type natural Tregs isolated from RankWt pregnant E7.5-8.5 donors (denoted as RankΔFoxn1_Treg). For the isolation of viable Tregs for the transplant, we generated RankWt dams that express GFP from the Foxp3 promoter (by crossing to reporter mice), and use the expression of GFP to mark and isolate bona fide Tregs and, in addition, Neuropilin1 to denote the thymic origin of the Tregs. Of note, RankWt as well as of RankΔFoxn1 dams mice also carried the GFP-Foxp3 transgene and where treated with vehicle solution (PBS) at day E0.5-2.5. Total RNA was extracted from the isolated gonadal white adipose tissue of the three described cohorts (RankWt_veh, RankΔFoxn1_veh, and RankΔFoxn1_Treg) and analyzed by Quant-seq. Our study shows how the presence of Rank receptors in the thymic epithelium, functioning via natural Tregs, regulate the inflammatory and metabolic pathways implicated in adipose tissue biology during pregnancy.

2020-10-05 | GSE117112 | GEO

Analysis of gonadal fat from male control and adipocyte-specific LAMA4 knockout mice

Project description:To determine the transcriptomic effects of LAMA4 loss on adipose tissue structure and gene expression in two dietary paradigms, we assessed gonadal white adipose tissue of male control and adipocyte-specific LAMA4 knockout mice using a Quant-Seq strategy.

2022-08-21 | GSE179138 | GEO

Next generation sequencing of white adipose tissues from adipose FoxO1 knockout mice

Project description:FoxO1 is a transcription factor known to regulate metabolism and functions of different tissues. To study the role of FoxO1 in adipose biology, this study examined the transcript profile in inguinal and gonadal adipose tissues from conditional adipose FoxO1 knockout mice and floxed FoxO1 (control) mice.

2024-10-01 | GSE227591 | GEO

Effect PPARb/d knockout in white adipose tissue

Project description:Analysis of white adipose tissue of PPARb/d knockout mice. Data may point towards putative target genes of PPARb/d and thus the function of PPARb/d in white adipose tissue. Datasets were used to identify glycogen synthase 2 as novel PPAR target. Keywords: gene expression array-based, count

2007-07-04 | GSE8344 | GEO

Effect of ablation of Sfrp5 on gene expression in gonadal white adipose tissue

Project description:We identified secreted frizzled-related protein-5 (Sfrp5) as a transcript that is upregulated during adipocyte differentiation and that is increased in white adipose tissue (WAT) of obese mice, compared to lean mice. To investigate the function of sFRP5 in adipose tissue biology, we studied sFRP5Q27stop mice, in which ENU mutagenesis was used to create a premature stop codon at Gln27, thereby creating a likely null allele. Male wild-type or Sfrp5 KO (Q27Stop) mice were fed a high-fat diet from the ages of four weeks to twelve weeks. At twelve weeks of age, mice were euthanized. Total RNA was then isolated from gonadal WAT and RNA was analyzed by Affymetrix microarrays. Seven wild-type and eight Sfrp5 KO mice were used.

2012-04-24 | E-GEOD-37514 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data