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Epicardial Differentiation Drives Fibro-fatty Remodeling in Arrhythmogenic Cardiomyopathy

ABSTRACT: Epicardial Differentiation Drives Fibro-fatty Remodeling in Arrhythmogenic Cardiomyopathy

PROVIDER: PRJNA640316 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11607547_1.fastq.gz	Fastqsanger.gz
	SRR11607547_2.fastq.gz	Fastqsanger.gz
	SRR11607548_1.fastq.gz	Fastqsanger.gz
	SRR11607548_2.fastq.gz	Fastqsanger.gz
	SRR11607549_1.fastq.gz	Fastqsanger.gz

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Epicardial Differentiation Drives Fibro-fatty Remodeling in Arrhythmogenic Cardiomyopathy [scRNA-seq]

Project description:We performed single cell RNA sequencing (scRNAseq) on epicardial cells generated from human induced pluripotent stem cells (hiPSCs) of an arrhythmogenic cardiomyopathy patient and their PKP2 reverted isogenic control. The goal of this experiment was to analyze the process of epicardial to fibro-fatty celluar differentiation in diseased cells and compare the cellular transcirptomes of diseased and healthy cells.

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Epicardial Differentiation Drives Fibro-fatty Remodeling in Arrhythmogenic Cardiomyopathy [bulk RNA-seq]

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