Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Manipulative experiment on Ulva australis surface-associated microbiome

ABSTRACT: Manipulative experiment on Ulva australis surface-associated bacterial community Raw sequence reads

PROVIDER: PRJNA640945 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12072800_1.fastq.gz	Fastqsanger.gz
	SRR12072800_2.fastq.gz	Fastqsanger.gz
	SRR12072801_1.fastq.gz	Fastqsanger.gz
	SRR12072801_2.fastq.gz	Fastqsanger.gz
	SRR12072802_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 126

Similar Datasets

Subversion of host innate immunity by Rickettsia australis via a modified autophagic response in macrophages

Project description:We recently reported that the in vitro and in vivo survival of Rickettsia australis are Atg5-dependent, in association with an inhibited level of anti-rickettsial cytokine, IL-1β. In the present study, we sought to investigate how R. australis interacts with host innate immunity via an Atg5-dependent autophagic response. We found that the serum levels of IFN-γ and G-CSF in R. australis-infected Atg5flox/floxLyz-Cre mice were significantly less compared to Atg5flox/flox mice, accompanied by significantly lower rickettsial loads in tissues with inflammatory cellular infiltrations including neutrophils. R. australis infection differentially regulated a significant number of genes in bone marrow-derived macrophages (BMMs) in an Atg5-depdent fashion as determined by RNA sequencing and Ingenuity Pathway Analysis, including genes in the molecular networks of IL-1 family cytokines and PI3K-Akt-mTOR. The secretion levels of inflammatory cytokines, such as IL-1α, IL-18, TNF-α, and IL-6, by R. australis-infected Atg5flox/floxLyz-Cre BMMs were significantly greater compared to infected Atg5flox/flox BMMs. Interestingly, R. australis significantly increased the levels of phosphorylated mTOR and P70S6K at a time when the autophagic response is induced. Rapamycin treatment nearly abolished the phosphorylated mTOR and P70S6K but did not promote significant autophagic flux during R. australis infection. These results highlight that R. australis modulates an Atg5-dependent autophagic response, which is not sensitive to regulation by mTORC1 signaling in macrophages. Overall, we demonstrate that R. australis counteracts host innate immunity including IL-1β-dependent inflammatory response to support the bacterial survival via an mTORC1-resistant autophagic response in macrophages.

2021-04-06 | GSE171160 | GEO

Ulva australis possible biotechnological applications

Project description:Exploring Ulva australis Areschoug for possible biotechnological applications: In vitro antioxidant and enzymatic inhibitory properties and fatty acids contents

| PRJEB34854 | ENA

Ulva prolifera, Ulva flexuosa, Ulva linza and Ulva compressa

Project description:Ulva prolifera, Ulva flexuosa, Ulva linza and Ulva compressa Raw sequence reads

| PRJNA512140 | ENA

Ulva prolifera

Project description:Stress Experiment on Ulva prolifera by Sodium Percarbonate Solution

| PRJNA1090908 | ENA

De novo transcriptome assembly for desiccation tolerance in intertidal seaweed species Ulva lactuca

Project description:This study aimed at identification of genetic regulations for desiccation tolerance in intertidal seaweed species Ulva lactuca most commonly experienced phenomenon of intertidal communities.

2018-04-17 | GSE97868 | GEO

Ulva

Project description:Ulva sp. overview

| PRJNA704174 | ENA

Transcriptome level regulations for desiccation and submergence tolerance in intertidal seaweed species Ulva lactuca

Project description:This study aimed at identification of genetic regulations for desiccation and submergence tolerance in intertidal seaweed species Ulva lactuca which arisies periodically due to tidal rhythms.

2018-04-13 | GSE97769 | GEO

Craspedostauros australis frustule associated components analysis

Project description:The biomolecular composition of diatom underwater adhesives remains unknown as does the precise mechanism by which the secretion of adhesive material from the raphe slit is coupled to an intracellular motor that provides the force for cell motility. In this study we have characterized the previously identified frustule associated components (FACs) from the common fouling diatom Craspedostauors australis and demonstrated that they form a continuous cell wall coating. The FACs are encoded by a single polypeptide (caFAP1) that has a domain structure of alternating cysteine-rich and PTS-rich regions which is reminiscent of the gel-forming mucins. CaFAP1 is notably absent from the raphe slit and therefore does not play a direct role in cell adhesion and motility but may rather play an important role in lubrication and self-cleaning that is required for epipsammic benthic diatoms that grow attached to sand grains, or moving through sand.

2023-01-09 | PXD026968 | Pride

Coastal Mediterranean Sea surface prokaryotes: Biodegradation experiment

Project description:Coastal Mediterranean Sea surface prokaryotes: Biodegradation experiment Raw sequence reads

| PRJNA629904 | ENA

Ulva armoricana

Project description:Ulva armoricana

| PRJNA894635 | ENA