Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Memory-induced epigenome in Huntington's disease (HD) mice [ChIP-seq]

ABSTRACT: Memory-induced epigenome in Huntington's disease (HD) mice [ChIP-seq]

PROVIDER: PRJNA660042 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12541900.fastq.gz	Fastqsanger.gz
	SRR12541901.fastq.gz	Fastqsanger.gz
	SRR12541902.fastq.gz	Fastqsanger.gz
	SRR12541903.fastq.gz	Fastqsanger.gz
	SRR12541905.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 44

Similar Datasets

Memory-induced epigenome in Huntington's disease (HD) mice [ChIP-seq]

Project description:Evaluation of the effect of procedural memory using the double-H maze (DH) on striatal epigenome in HD R6/1 mice

2022-10-06 | GSE157083 | GEO

Memory-induced transcriptome in Huntington's disease (HD) mice [RNA-seq]

Project description:Memory-induced transcriptome in Huntington's disease (HD) mice [RNA-seq]

| PRJNA660056 | ENA

Memory-induced 3D chromatin architecture in Huntington's disease (HD) mice [4C-seq]

Project description:Memory-induced 3D chromatin architecture in Huntington's disease (HD) mice [4C-seq]

| PRJNA660022 | ENA

Memory-induced transcriptome in Huntington's disease (HD) mice [RNA-seq]

Project description:Evaluation of the effect of procedural memory using the double-H maze (DH) on striatal and hippocampal transcriptome in HD R6/1 mice

2022-10-06 | GSE157099 | GEO

Memory-induced 3D chromatin architecture in Huntington's disease (HD) mice [4C-seq]

Project description:Evaluation of the effect of procedural memory using the double-H maze (DH) on striatal 3D chromatin architecture in HD R6/1 mice

2022-10-06 | GSE157076 | GEO

Hdac4 interactome in Huntington's Disease

Project description:Hdac4 has been found to modulate symptoms in Huntington's Disease (HD) mouse models through an uknown mechanism unrelated to any enzymatic activity. We investigated the protein-protein interactions to gain insight into the role of Hdac4 in HD.

2019-05-01 | PXD011845 | Pride

Neurobiological Predictors of Huntington's Disease Onset (Predict-HD)

Project description:Neurobiological Predictors of Huntington's Disease Onset (Predict-HD)

| PRJNA75985 | ENA

Analysis of FOXO3 human targets in Huntington's disease neural stem cells: FOXO3 nuclear induction [ChIP-Seq]

Project description:We report the identification of F0X03 targets in human Huntington's disease neural stem cells. To this end, we generated FOXO3 ChIP-seq data upon FOXO3 nuclear induction in human Huntington's disease (HD) and CAG-corrected (C116) neural stem cells.

2021-01-30 | GSE109871 | GEO

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (ChIP-seq)

Project description:Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain. Genome-wide analysis showed a novel chromatin signature for this mark. Reducing the levels of the H3K4 demethylase SMCX/Jarid1c in primary neurons reversed down-regulation of key neuronal genes caused by mutant Huntingtin (Htt) expression. Finally, reduction of SMCX/Jarid1c in primary neurons from BACHD mice or the single Jarid1 in a Drosophila HD model was protective. Therefore, targeting this epigenetic signature may be an effective strategy to ameliorate the consequences of HD. ChIP-seq for H3K4me3 in wild type and R6/2 cortex and striatum at 8 and 12 weeks.

2013-07-18 | E-GEOD-48960 | biostudies-arrayexpress

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (ChIP-seq)

2013-07-18 | GSE48960 | GEO