Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Acinetobacter

ABSTRACT: Whole genome sequencing of carbapenem non-susceptible Acinetobacter in a Singapore hospital

PROVIDER: PRJNA664284 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR25241259_1.fastq.gz	Fastqsanger.gz
	SRR25241259_2.fastq.gz	Fastqsanger.gz
	SRR25241260_1.fastq.gz	Fastqsanger.gz
	SRR25241260_2.fastq.gz	Fastqsanger.gz
	SRR25241261_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 50

Similar Datasets

Pseudomonas

Project description:Whole genome sequencing of carbapenem non-susceptible Pseudomonas in a Singapore hospital

| PRJNA656645 | ENA

Enterobacteriaceae

Project description:Whole genome sequencing of carbapenem non-susceptible Enterobacterales in a Singapore hospital

| PRJNA577535 | ENA

Acinetobacter

Project description:Acinetobacter whole-genome sequencing for hospital epidemology

| PRJNA297777 | ENA

Acinetobacter baumannii

Project description:tigecycline-non-susceptible Acinetobacter baumannii

| PRJNA672213 | ENA

Carbapenem-susceptible Gram negative bacteria

Project description:Carbapenem-susceptible Gram negative bacteria sequences from a Singapore Hospital

| PRJNA1281836 | ENA

Characterization functional of AcoN-like negative regulator protein from Acetoin cluster in Acinetobacter spp. Strains

Project description:Studies of expression of mechanims of defense of the Acinetobacter sp.5-2Ac.02 from airborne hospital environment under stress conditions, such as SOS response (ROS response, heavy metals resistant mechanisms, peptides), as well as Quorum network (acetoin cluster and aromatics biodegradation cluster). Characterization functional of AcoN-like as negative regulator protein from acetoin cluster in Acinetobacter spp. Strains

2019-07-16 | GSE120392 | GEO

Six strains of Acinetobacter Baumannii: RNAseq data analysis

Project description:We performed RNAseq for gene expression analysis for six strains of Acinetobacter Baumannii isolated from blood samples (defined as strains 1, 2, 3, 4 and 6) of patients hospitalized at the University Hospital \\"San Giovanni di Dio e Ruggi d'Aragona\\" (Salerno, Italy)

2023-09-01 | E-MTAB-13274 | biostudies-arrayexpress

Acinetobacter baumannii

Project description:Whole genome sequencing of Carbapenem resistant Acinetobacter baumannii

| PRJNA604897 | ENA

Multi-omics approach to study global changes in a triclosan mutant strain of Acinetobacter baumannii ATCC 17978.

Project description:Acinetobacter baumannii AB042, a triclosan-resistant mutant, was examined for modulated gene expression using whole genome sequencing, transcriptomics, and proteomics in order to understand the mechanism of triclosan-resistance as well as its impact on A. Baumannii.

2016-09-28 | GSE87398 | GEO

Acinetobacter baumannii response to cefiderocol challenge in human urine

Project description:Cefiderocol (CFDC) is a novel chlorocatechol-substituted siderophore approved to treat complicated urinary tract infections and for hospital-acquired and ventilator-acquired pneumonia. In previous work, human fluids, were shown to increase the minimum inhibitory concentration (MICs) of Acinetobacter baumannii against CFDC and reduce the expression of genes related to iron uptake systems, which could explain the need for higher concentrations of CFDC to exert inhibitory action. Herein, we analyzed the impact of human urine (HU), which contains low albumin concentrations, on the expression of iron-uptake related genes and MIC values of two carbapenem-resistant A. baumannii. Levels of resistance to CFDC were not modified by HU in strain AMA40 but were reduced in the case of strain AB5075. Testing other carbapenem-resistant A. baumannii isolates showed that the CFDC MICs were unmodified or reduced in the presence of HU. The expression of piuA, pirA, bauA, and bfnH determined by qRT-PCR was enhanced in both strains when HU was present in the culture medium. All four tested genes are involved in recognizing ferric siderophore complexes or internalization into the cell’s cytosol. In contrast, the effect of HU on genes associated with resistance to β-lactams, antibiotics commonly used to treat urinary tract infections caused by A. baumannii, was variable; the transcriptional analysis of pbp1, pbp3, blaOXA-51-like, blaADC, and blaNDM-1 showed significant variation. In summary, HU, probably due to the albumin and free iron content, does not adversely impact or slightly improves the activity of CFDC when tested against A. baumannii in urine in contrast to other human bodily fluids.

2022-06-01 | GSE201259 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data