Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Kids First:Genomic Analysis of Esophageal Atresia and Tracheoesophageal Fistulas and Associated Congenital Anomalies

ABSTRACT: Kids First:Genomic Analysis of Esophageal Atresia and Tracheoesophageal Fistulas and Associated Congenital Anomalies

PROVIDER: PRJNA671195 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Kids First:Genomic Analysis of Esophageal Atresia and Tracheoesophageal Fistulas and Associated Congenital Anomalies

Project description:Kids First:Genomic Analysis of Esophageal Atresia and Tracheoesophageal Fistulas and Associated Congenital Anomalies

| PRJNA671194 | ENA

Kids First: Genomic Analysis of Esophageal Atresia and Tracheoesophageal Fistulas and Associated Congenital Anomalies

Project description:<p>The Gabriella Miller Kids First Pediatric Research Program (Kids First) is a trans-NIH effort initiated in response to the 2014 Gabriella Miller Kids First Research Act and supported by the NIH Common Fund. This program focuses on gene discovery in pediatric cancers and structural birth defects and the development of the Gabriella Miller Kids First Pediatric Data Resource (Kids First Data Resource).</p><p> </p><div> </div><div>All of the WGS and phenotypic data from this study are accessible through dbGaP and <a href="https://kidsfirstdrc.org/" target="_blank">kidsfirstdrc.org</a>, where other Kids First datasets can also be accessed. </div><div> </div><div><br></div><div>Esophageal atresia/tracheoesophageal fistula (EA/TEF) is a rare and complex aerodigestive congenital anomaly with an estimated incidence of 1 in 2500 to 1 in 4000 live births. We propose to elucidate the underlying genomic architecture of EA/TEF by performing whole genome sequencing to characterize new clinical syndromes associated with EA/TEF to provide more accurate clinical prognostic information. </div><div><br></div><p></p>

| phs002161 | dbGaP

Kids First: CHARGE Syndrome, Related Conditions and Structural Anomalies

Project description:Kids First: CHARGE Syndrome, Related Conditions and Structural Anomalies

| PRJNA760560 | ENA

Kids First: CHARGE Syndrome, Related Conditions and Structural Anomalies

Project description:Kids First: CHARGE Syndrome, Related Conditions and Structural Anomalies

| PRJNA760561 | ENA

PBMC immune transcriptome analysis in kids fed on doe's milk(Control) versus kids fed on replacer milk (Test)

Project description:To study differential expression of genes in kids fed on does milk(Control) versus kids fed on replacer milk (Test)

2025-01-31 | GSE223592 | GEO

PBMC immune transcriptome analysis in kids fed on doe's milk(Control) versus kids fed on replacer milk (Test) post-PPR vaccination

Project description:To study differential expression of genes in kids fed on doe's milk(Control) versus kids fed on replacer milk (Test) post PPR Vaccination

2025-01-31 | GSE223506 | GEO

Tracheoesophageal fistula characterisation

Project description:Esophageal atresia and tracheoesophageal fistula (EA/TEF) are relatively frequently occurring foregut malformations with a largely unknown etiology. EA/TEF is thought to have a strong genetic component and several genes have been proven to be involved in syndromic EA/TEF. However, it is not clear which biological processes or gene networks are disturbed. To gain more insight in the origin of the TEF, we aimed to examine and describe TEF composition using a combination of whole-genome transcription profiling and (immuno-) histochemical stainings. We hypothesized that such characterization of human TEFs provides insight in the molecular and mechanistic etiology of EA/TEF. Data analysis was carried out using BRB-array tools version 4.6.0 (October 2018) in combination with R version 3.5.1 (July 2018). For each probe set, the geometric mean of the hybridization intensities of all samples was calculated. The level of expression of each probe set was determined relative to this geometric mean and logarithmically transformed (on a base 2 scale) to ascribe equal weight to gene-expression levels with similar relative distances to the geometric mean.

2020-10-30 | GSE148247 | GEO

Tracheoesophageal fistula characterisation

Project description:Tracheoesophageal fistula characterisation

| PRJNA623592 | ENA

Kids First: Genetic Spectrum of Vascular Anomalies, Overgrowth and Structural Birth Defects

Project description:Kids First: Genetic Spectrum of Vascular Anomalies, Overgrowth and Structural Birth Defects

| PRJNA760636 | ENA

Genome sequencing of oesophagus atresia families

Project description:To gain insight into gene variants and genes associated with isolated Oesophageal atresia (OA) we conducted whole genome sequencing on samples from three families with recurrent cases affected by congenital and isolated tracheoesophageal fistula (TEF).

| EGAS00001004394 | EGA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data