Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Complete chloroplast genome sequence of the medicinal plant ramie (Boehmeria nivea L. gaud)

PROVIDER: PRJNA688987 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13433988_1.fastq.gz	Fastqsanger.gz
	SRR13433988_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Project description:The characterization of the complete chloroplast genome sequence of the medicinal plant ramie (Boehmeria nivea L. gaud)

| PRJNA689630 | ENA

Project description:The description of the complete chloroplast genome sequence of the medicinal plant ramie (Boehmeria nivea L. gaud)

| PRJNA689705 | ENA

Boehmeria nivea (L.) Gaud. Ameliorates Oxidative stress-mediated Inflammatory Responses and Apoptosis in LPS/CSC-induced Chronic Obstructive Pulmonary Disease Mouse Model

Project description:Introduction: Boehmeria nivea (L.) Gaud. has traditionally been regarded as a functional food with applications in various inflammatory disorders. However, its role in chronic obstructive pulmonary disease (COPD) has not yet been clarified. Methods: In this study, the preventive efficacy of the ethyl acetate fraction of B. nivea (L.) Gaud. leaves (EA-BN) was evaluated in a COPD model established by intranasal instillation of lipopolysaccharide (LPS; 0.5 mg/kg body weight) and cigarette smoke condensate (CSC; 12.5 mg/kg body weight) in male C57BL/6N mice. The experimental groups received dexamethasone (3 mg/kg) as a positive control or EA-BN at doses of 200 mg/kg. Results: EA-BN administration significantly reduced T helper 1 cytokine levels and decreased macrophage and neutrophil counts in bronchoalveolar lavage fluid. Histological analyses revealed that EA-BN mitigated alveolar destruction and inflammatory infiltration, whereas pulmonary function tests demonstrated improvements in the FEV0.1/FVC ratio and lung elastance in the LPS/CSC-induced COPD. Additionally, EA-BN alleviated oxidative stress by promoting the nuclear translocation of Nrf2 and enhancing the expression of its downstream targets, HO-1 and NQO1, leading to a reduction in reactive oxygen species and nitric oxide production. EA-BN downregulated thioredoxin-interacting protein and NLRP3 inflammasome activation, thereby suppressing caspase-1 and IL-1β expression, and also attenuated apoptosis by modulating the Bax/Bcl-2/caspase-3 pathway. Discussion: Collectively, these findings suggest that EA-BN possesses antioxidant, anti-inflammatory, and anti-apoptotic properties, supporting its potential as a preventive agent against COPD.

2026-01-13 | GSE315863 | GEO

Project description:The complete chloroplast genome sequence of medicinal plant

| PRJNA885109 | ENA

Genome-wide transcriptome analysis to identify genes involved in adventitious root formation of ramie (Boehmeria nivea L. Gaud) cutting

Project description:Genome-wide transcriptome analysis to identify genes involved in adventitious root formation of ramie (Boehmeria nivea L. Gaud) cutting

| PRJNA476939 | ENA

Boehmeria nivea

Project description:Boehmeria nivea Raw sequence reads

| PRJNA390675 | ENA

Boehmeria nivea

Project description:Boehmeria nivea Raw sequence reads

| PRJNA489320 | ENA

Boehmeria nivea

Project description:Boehmeria nivea Raw sequence reads

| PRJNA386617 | ENA

Boehmeria nivea

Project description:Boehmeria nivea Raw sequence reads