Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single cell atlas of epithelial and stromal cell heterogeneity by lobe and strain in the mouse prostate

ABSTRACT: Single cell atlas of epithelial and stromal cell heterogeneity by lobe and strain in the mouse prostate

PROVIDER: PRJNA695577 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13575222_1.fastq.gz	Fastqsanger.gz
	SRR13575222_2.fastq.gz	Fastqsanger.gz
	SRR13575223_1.fastq.gz	Fastqsanger.gz
	SRR13575223_2.fastq.gz	Fastqsanger.gz
	SRR13575224_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 40

Similar Datasets

Single-cell transcriptome Atlas reveals embryonic endothelial heterogeneity

Project description:Single-cell transcriptome Atlas reveals embryonic endothelial heterogeneity

| PRJNA896490 | ENA

The single cell atlas of human endometrial stromal cells

Project description:The single cell atlas of human endometrial stromal cells

| PRJNA802678 | ENA

A Rat Liver Cell Atlas Reveals Intrahepatic Myeloid Heterogeneity.

Project description:A Rat Liver Cell Atlas Reveals Intrahepatic Myeloid Heterogeneity.

| PRJNA908768 | ENA

Stromal Fibroblasts Drive Single Cell Heterogeneity in Pancreatic Cancer

Project description:Stromal Fibroblasts Drive Single Cell Heterogeneity in Pancreatic Cancer

| PRJNA464359 | ENA

A healthy human liver cell atlas reveals hepatic stellate cell heterogeneity

Project description:A healthy human liver cell atlas reveals hepatic stellate cell heterogeneity

| PRJNA666353 | ENA

A single cell transcriptome atlas of Human thymic stromal compartment

Project description:A single cell transcriptome atlas of Human thymic stromal compartment

| PRJNA670375 | ENA

A Human Liver Cell Atlas reveals Heterogeneity and Epithelial Progenitors

Project description:A Human Liver Cell Atlas reveals Heterogeneity and Epithelial Progenitors

| PRJNA511895 | ENA

Comparative single-cell transcriptional and proteomic atlas of clinical-grade injectable mesenchymal source tissues

Project description:Bone marrow aspirate concentrate (BMAC) and adipose-derived stromal vascular fraction (ADSVF) are the most marketed stem cell therapies to treat a variety of conditions in the general population and elite athletes. Both tissues have been used interchangeably clinically even though their detailed composition, heterogeneity, and mechanisms of action have neither been rigorously inventoried nor compared. This lack of information has prevented investigations into ideal dosages and has facilitated anecdata and misinformation. Here, we analyzed single-cell transcriptomes, proteomes, and flow cytometry profiles from paired clinical-grade BMAC and ADSVF. This comparative transcriptional atlas challenges the prevalent notion that there is one therapeutic cell type present in both tissues. We also provide data of surface markers that may enable isolation and investigation of cell (sub)populations. Furthermore, the proteome atlas highlights intertissue and interpatient heterogeneity of injected proteins with potentially regenerative or immunomodulatory capacities.

2024-07-25 | PXD037632 | Pride

Lymph Node Stromal Cell Responses to Perinatal T Cell Waves, A Temporal Atlas

Project description:Lymph Node Stromal Cell Responses to Perinatal T Cell Waves, A Temporal Atlas

| PRJNA1024477 | ENA

Single-Cell transcriptomes of murine Bone Marrow Stromal Cells Reveal Niche-Associated Heterogeneity

Project description:Bone marrow (BM) stromal cells are important in the development and maintenance of cells of the immune system. Using single cell RNA sequencing, we here explore the functional and phenotypic heterogeneity of individual transcriptomes of 1,167 murine BM mesenchymal stromal cells. These cells exhibit a tremendous heterogeneity of gene expression, which precludes the identification of defined subpopulations. However, according to the expression of 108 genes involved in the communication of stromal cells with hematopoietic cells, we have identified 14 non-overlapping subpopulations, with distinct cytokine or chemokine gene expression signatures. With respect to the maintenance of subsets of immune memory cells by stromal cells, we identify distinct subpopulations expressing IL7, IL15 and Tnfsf13b. Together, this study provides a comprehensive dissection of the BM stromal heterogeneity at the single cell transcriptome level and provides a basis to understand their lifestyle and their role as organizers of niches for the long-term maintenance of immune cells.

2019-05-17 | GSE131365 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data