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STAT3 maintains skin barrier integrity by modulating SPINK5 and KLK5 expression in keratinocytes

ABSTRACT: STAT3 maintains skin barrier integrity by modulating SPINK5 and KLK5 expression in keratinocytes

PROVIDER: PRJNA699446 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR13627334.fastq.gz	Fastqsanger.gz
	SRR13627335.fastq.gz	Fastqsanger.gz
	SRR13627336.fastq.gz	Fastqsanger.gz
	SRR13627337.fastq.gz	Fastqsanger.gz
	SRR13627338.fastq.gz	Fastqsanger.gz

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STAT3 maintains skin barrier integrity by modulating SPINK5 and KLK5 expression in keratinocytes

Project description:We elucidated the potential role of STAT3 in the skin barrier and its effect on kallikrein-related peptidase 5 (KLK5) and serine protease inhibitor Kazal-type 5 (SPINK5) expression using a mouse model with keratinocyte-specific ablation of STAT3.

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