Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Cepba dependent gene expression in hematopoietic progenitors from mice treated with interleukin-1

ABSTRACT: Cepba dependent gene expression in hematopoietic progenitors from mice treated with interleukin-1

PROVIDER: PRJNA701444 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13690433_1.fastq.gz	Fastqsanger.gz
	SRR13690433_2.fastq.gz	Fastqsanger.gz
	SRR13690434_1.fastq.gz	Fastqsanger.gz
	SRR13690434_2.fastq.gz	Fastqsanger.gz
	SRR13690435_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 48

Similar Datasets

Cepba dependent gene expression in hematopoietic progenitors from mice treated with interleukin-1

Project description:We analyzed gene expression in Cebpa+/+ or CebpaΔ/Δ multipotent progenitors (MPP3) from mice treated with or without interleukin-1-beta.

2021-03-25 | GSE166629 | GEO

BLUEPRINT hematopoietic progenitors

Project description:BLUEPRINT hematopoietic progenitors

| PRJNA343828 | ENA

Mass spectrometry analysis of mouse hematopoietic stem cells and their progenitors reveals differential expression within and between proteome and transcriptome throughout adult and aged hematopoiesis

Project description:mass spectrometry analysis of aged and adult hematopoietic stem cells, multipotent progenitors and oligopotent progenitors

2021-07-24 | PXD017442 | Pride

Phosphoproteome of fibro/adipogenic progenitors treated by Musclin in vitro

Project description:Fibro/adipogenic progenitors were isolated and treated by Musclin for 48 hours in vitro.

2021-09-14 | PXD028468 |

Epigenetic profiling of hematopoietic progenitors [Bulk_ATACseq_Prog]

Project description:Epigenetic profiling of hematopoietic progenitors [Bulk_ATACseq_Prog]

| PRJNA777799 | ENA

Hematopoietic progenitors and lineage cells - sRNA

Project description:Hematopoietic progenitors and lineage cells - sRNA

| PRJEB7752 | ENA

Hematopoietic progenitors and lineage cells - mRNA

Project description:Hematopoietic progenitors and lineage cells - mRNA

| PRJEB7754 | ENA

Interleukin-33 contributes to anemia of chronic inflammation by inhibiting differentiation of erythroid progenitors

Project description:Mature blood cells are produced continuously from hematopoietic stem and progenitor cells (HSPCs) in the bone marrow (BM). During chronic inflammation, this process may be perturbed by inflammatory cytokines acting on HSPCs to cause anemia of inflammatory disease. Among BM HSPCs, we found the receptor for interleukin (IL)-33, ST2, was expressed preferentially and highly on erythroid progenitors. Induction of inflammatory spondyloarthritis in mice increased IL-33 in BM plasma, and IL-33 was required for inflammation-dependent suppression of erythropoiesis in BM. Conversely, administration of IL-33 in healthy mice suppressed erythropoiesis, decreased hemoglobin expression, and caused anemia. Using purified erythroid progenitors in vitro, we showed that IL-33 directly inhibited terminal maturation. This effect was dependent on NF-kB activation and was associated with altered signalling events downstream of the erythropoietin receptor. Accordingly, IL-33 also suppressed erythropoietin-induced stress erythropoiesis in vivo. These results reveal a role for IL-33 in regulation of erythropoiesis during inflammatory disease and define a new target for its treatment.

2020-05-15 | GSE141480 | GEO

Hematopoietic progenitors and lineage cells - mRNA

Project description:Sequencing and analysis of hematopoietic progenitors and lineage cells

2015-04-28 | E-MTAB-3079 | biostudies-arrayexpress

Hematopoietic progenitors and lineage cells - sRNA

Project description:Sequencing and analysis of hematopoietic progenitors and lineage cells, small RNA

2015-11-25 | E-MTAB-3080 | biostudies-arrayexpress