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Chromosome 21-encoded miR-125b cooperates with GATA1s in trisomy 21-associated megakaryoblastic leukemia by targeting the megakaryocytic transcription factor ARID3A III

ABSTRACT: Chromosome 21-encoded miR-125b cooperates with GATA1s in trisomy 21-associated megakaryoblastic leukemia by targeting the megakaryocytic transcription factor ARID3A III

PROVIDER: PRJNA717777 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14083385_1.fastq.gz	Fastqsanger.gz
	SRR14083385_2.fastq.gz	Fastqsanger.gz
	SRR14083386_1.fastq.gz	Fastqsanger.gz
	SRR14083386_2.fastq.gz	Fastqsanger.gz
	SRR14083387_1.fastq.gz	Fastqsanger.gz

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Chromosome 21-encoded miR-125b cooperates with GATA1s in trisomy 21-associated megakaryoblastic leukemia by targeting the megakaryocytic transcription factor ARID3A I

Project description:The purpose of this study was to decipher the molecular network underlying the synergy between the GATA1s mutation and loss of Arid3a. We used gene expression profiling (RNA-Seq) to evaluate gene expression changes upon gain and loss of Arid3a in the context of the Gata1s mutation

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Expression data from transgenic ERG, GATA1s KI and ERG/GATA1s fetal livers

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