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Ovis aries breed:East Friesian

ABSTRACT: East Friesian sheep whole genome sequencing and de novo assembly

PROVIDER: PRJNA721520 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
		Other
	SRR14226310_1.fastq.gz	Fastqsanger.gz
	SRR14226310_2.fastq.gz	Fastqsanger.gz

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Ovis aries isolate:LY-2023 | breed:East Friesian sheep

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2014-06-06 | E-GEOD-56643 | biostudies-arrayexpress

MeDIP sequencing of Ovis aries

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Linkage disequilibrium in Brazilian Santa Ines breed, Ovis aries.

Project description:For genomic selection to be successful, there must be sufficient linkage disequilibrium between the markers and the causal mutations. The objectives of this study were to evaluate the extent of LD in ovine using the Santa Inês breed and to infer the minimum number of markers required to reach reasonable prediction accuracy. In total, 38,168 SNPs and 395 samples were used. The mean LD between adjacent marker pairs measured by r2 and |D'| were 0.166 and 0.617, respectively. LD values between adjacent marker pairs ranged from 0.135 to 0.194 and from 0.568 to 0.650 for r2 for |D'| across all chromosomes. The average r2 between all pairwise SNPs on each chromosome was 0.018. SNPs separated by between 0.10 to 0.20 Mb had an estimated average r2 equal to 0.1033. The identified haplotype blocks consisted of 2 to 21 markers. Moreover, estimates of average coefficients of inbreeding and effective population size were 0.04 and 96, respectively. LD estimated in this study was lower than that reported in other species and was characterized by short haplotype blocks. Our results suggest that the use of a higher density SNP panel is recommended for the implementation of genomic selection in the Santa Inês breed.

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Project description:EAST FRIESIAN SHEEP

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Identification of Prolificacy-related Differentially Expressed Proteins from Sheep (Ovis aries) Hypothalamus by Comparative Proteomics

Project description:Reproduction, as a physiologically complex process, can significantly affect the development of the sheep industry. However, a lack of overall understanding to sheep fecundity has long blocked the progress in sheep breeding and husbandry. Herein, in present study, we aimed to identify differentially expressed proteins (DEPs) from hypothalamus in sheep without FecB mutation in two comparison groups: polytocous (PF) versus (vs.) monotocous (MF) sheep at follicular phase and polytocous (PL) vs. monotocous (ML) sheep at luteal phase,expecting to provide an alternative method to identify DEPs associated with sheep prolificacy from the hypothalamus.

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2016-04-26 | GSE69997 | GEO

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