Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: The complete chloroplast genome sequence of Amaranthus dubiuspalmeri S Mart. ex Thell.

PROVIDER: PRJNA741594 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14920259_1.fastq.gz	Fastqsanger.gz
	SRR14920259_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Project description:Complete chloroplast genome of Amaranthus tricolor

| PRJNA801093 | ENA

Torenia flava

Project description:Complete chloroplast genome sequence of Torenia flava Buch.-Ham. ex Benth.

| PRJNA862093 | ENA

Project description:The complete chloroplast genome sequence of Heuchera micrantha Douglas ex Lindl.(Saxifragaceae)

| PRJNA780969 | ENA

Project description:The complete chloroplast genome sequence of Meliosma oldhamii Miq. ex Maxim. (Sabiaceae)

| PRJNA747830 | ENA

Plastid genome of Cerastium davuricum

Project description:Complete chloroplast genome sequence

| PRJEB84197 | ENA

Project description:Complete chloroplast genome sequence

| PRJNA947379 | ENA

T-cell receptor/CD28-targeted Immunotherapeutics Generate Functional Melanoma- or HIV-specific Responses by Selectively Driving Naïve T-Cell Expansion

Project description:Adoptive cell transfer (ACT), an increasingly used immunotherapeutic approach for the treatment of cancer and infectious diseases, typically infuses antigen-specific CD8+ T cells obtained after ex vivo stimulation with patient-derived dendritic cells (DC) loaded with defined peptides. However, broader use of this approach is limited by logistical complexity, variability, cost, and inconsistency in cell quality. To overcome these limitations, we developed a dimeric protein scaffold-based antigen-presentation platform, Immuno-STAT (IST), which delivers peptide-specific TCR activation and costimulatory signaling to robustly expand highly functional antigen-specific CD8+ T cells. We demonstrate that delivering TCR and CD28 signals by IST selectively activates and expands highly functional cytotoxic CD8+ T cells from the naïve CD8+ T cell repertoire specific for the melanoma-associated MART-1 antigen and the HIV-associated SL9 antigen. While naïve MART-1-specific CD8+ T cells were expanded by both MART-1-peptide loaded DC and MART-1-specific IST, naïve SL9-specific CD8+ T cells were expanded only by SL9-specific IST and not by SL9-peptide loaded DC. By enabling ex-vivo expansion of naïve antigen-specific T cells without generation of autologous DC, IST may overcome the practical hurdles limiting the wider use of ACT and expand its use as a therapeutic strategy for both cancer and infectious disease.

2025-07-21 | GSE286286 | GEO